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CACNA1B gene

Known as: CaV2.2, CACNL1A5, CALCIUM CHANNEL, L TYPE, ALPHA-1 POLYPEPTIDE, ISOFORM 5 
National Institutes of Health

Papers overview

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2018
2018
An understudied symptom of the genetic disorder Neurofibromatosis type 1 (NF1) is chronic idiopathic pain. We used targeted… Expand
2015
2015
The neuronal circuit remodels during development as well as in human neuropathologies such as epilepsy. Neurite outgrowth is an… Expand
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2015
2015
Myoclonus-dystonia (M-D) is a very rare movement disorder, caused in ∼30–50% of cases by mutations in SGCE. The CACNA1B variant c… Expand
2014
2014
The pathway through which preferentially GqPCRs inhibit CaV2.2 channels depends on which β subunits are present. 
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2014
2014
Peripheral nerve injury induces neuropathic pain which is characterized by tactile allodynia and thermal hyperalgesia. N-type… Expand
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Review
2013
Review
2013
Chronic neuropathic pain management is a worldwide concern. Pharmaceutical companies globally have historically targeted ion… Expand
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2013
2013
The axon/dendrite specification collapsin response mediator protein 2 (CRMP2) bidirectionally modulates N-type voltage-gated Ca2… Expand
2013
2013
The fusion of synaptic vesicles (SVs) at the presynaptic transmitter release face is gated by Ca2+ influx from nearby voltage… Expand
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Highly Cited
2009
Highly Cited
2009
Genome-wide association (GWAS) analyses have identified susceptibility loci for many diseases, but most risk for any complex… Expand
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1995
1995
The alpha 1 subunit genes encoding voltage-dependent Ca2+ channels are members of a gene family. We have used human brain cDNA… Expand