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CAB39 gene

Known as: MO25-ALPHA, CALCIUM-BINDING PROTEIN 39, CGI-66 
 
National Institutes of Health

Papers overview

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Review
2016
Review
2016
Protein kinases are known primarily for their ability to phosphorylate protein substrates, which constitutes an essential… Expand
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Highly Cited
2015
Highly Cited
2015
LKB1 is activated by forming a heterotrimeric complex with STRAD and MO25. Recent studies suggest that LKB1 has pro-oncogenic… Expand
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Highly Cited
2012
Highly Cited
2012
The microRNA miR-451 is downregulated in gliomas, this has been suggested by several different research groups and is consistent… Expand
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Highly Cited
2011
Highly Cited
2011
Unc-51-like kinase 1 (Ulk1) plays a central role in autophagy induction. It forms a stable complex with Atg13 and focal adhesion… Expand
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Highly Cited
2010
Highly Cited
2010
To sustain tumor growth, cancer cells must be able to adapt to fluctuations in energy availability. We have identified a single… Expand
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Highly Cited
2009
Highly Cited
2009
The human Lkb1 kinase, encoded by the ortholog of the invertebrate Par4 polarity gene, is mutated in Peutz-Jeghers cancer… Expand
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Highly Cited
2009
Highly Cited
2009
LKB1 kinase is a tumor suppressor that is causally linked to Peutz-Jeghers syndrome. In complex with the pseudokinase STRAD and… Expand
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2009
2009
LKB1 is an upstream activating kinase for the AMP-activated protein kinase (AMPK) and at least 12 other AMPK-related kinases… Expand
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Highly Cited
2004
Highly Cited
2004
We recently demonstrated that the LKB1 tumour suppressor kinase, in complex with the pseudokinase STRAD and the scaffolding… Expand
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2004
2004
LKB1 complexed with MO25 and STRAD has been identified as an AMP-activated protein kinase kinase (AMPKK). We measured relative… Expand
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