CA1P

Known as: 1,2-Benzenediol, 3-methoxy-6-((1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl)-, 1,2-bis(dihydrogen Phosphate), Combretastatin A-1 bis(phosphate), Combretastatin A1 diphosphate 
The diphosphate prodrug of the stilbenoid combretastatin A1, originally isolated from the plant Combretum caffrum, with vascular-disrupting and… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Therapeutic targeting of the tumor vasculature that destroys preexisting blood vessels of the tumor and antiangiogenesis therapy… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 4
Is this relevant?
Review
2004
Review
2004
Vascular targeting agents (VTAs) for the treatment of cancer are designed to cause a rapid and selective shutdown of the blood… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • table 2
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Combretastatin A-4-phosphate (CA-4-P) is a tubulin-binding compound currently in clinical trial as a tumor vascular-targeting… (More)
Is this relevant?
Highly Cited
2002
Highly Cited
2002
The utility of combining the vascular targeting agents 5,6-dimethyl-xanthenone-4 acetic acid (DMXAA) and combretastatin A-4… (More)
Is this relevant?
Review
2001
Review
2001
Angiogenesis is a fundamental process in reproduction and wound healing. Under these conditions, neovascularization is tightly… (More)
  • table 1
  • table 2
  • table 3
  • table 4
  • table 5
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Selective induction of vascular damage within tumors represents an emerging approach to cancer treatment. Histological studies… (More)
  • figure 1
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1995
Highly Cited
1995
A series of stilbenes, based on combretastatin A-4, were synthesised. A structure-activity study was carried out to characterise… (More)
  • figure 2
  • figure 3
  • table I
  • table II
  • table III
Is this relevant?
Highly Cited
1993
Highly Cited
1993
The light-dependent regulation of ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) activity was studied in 16 species of… (More)
Is this relevant?
Highly Cited
1989
Highly Cited
1989
The African treeCombretum caffrum (Combretaceae) has been found to contain a powerful inhibitor of tubulin polymerization (IC502… (More)
Is this relevant?
Highly Cited
1989
Highly Cited
1989
Combretastatin A-4 (CS-A4), 3,4,5-trimethoxy-3'-hydroxy-4'-methoxy-(Z)-stilbene, and combretastatin A-2 (CS-A2), 3,4… (More)
Is this relevant?