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C8orf4 gene

Known as: TC-1, hTC-1, CHROMOSOME 8 OPEN READING FRAME 4 
National Institutes of Health

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Related topics

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FAM167A gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
Circular RNA circZFR contributes to papillary thyroid cancer cell proliferation and invasion by sponging miR-1261 and facilitating C8orf4 expression.
Highly Cited
2016
Highly Cited
2016
Epigenetic regulation of cyclooxygenase-2 by methylation of c8orf4 in pulmonary fibrosis
The present study demonstrates that hypermethylation and silencing of chromosome 8 open reading frame 4 (thyroid cancer protein 1… 
Highly Cited
2015
Highly Cited
2015
C8orf4 negatively regulates self-renewal of liver cancer stem cells via suppression of NOTCH2 signalling
Liver cancer stem cells (CSCs) harbour self-renewal and differentiation properties, accounting for chemotherapy resistance and… 
Highly Cited
2010
Highly Cited
2010
Adoptive Transfer of Tumor-Specific Tc17 Effector T Cells Controls the Growth of B16 Melanoma in Mice
In vitro generated OVA-specific IL-17–producing CD8 T effector cells (Tc17) from OT-1 mice, adoptively transferred into B16-OVA… 
Highly Cited
2004
Highly Cited
2004
TC-1 is a novel tumorigenic and natively disordered protein associated with thyroid cancer.
A novel gene, thyroid cancer 1 (TC-1), was found recently to be overexpressed in thyroid cancer. TC-1 shows no homology to any of… 
Highly Cited
2000
Highly Cited
2000
Cloning of TC-1 (C8orf4), a novel gene found to be overexpressed in thyroid cancer.
A novel gene highly expressed in thyroid cancer, designated TC-1 (thyroid cancer-1), was cloned from suppression subtractive… 
Highly Cited
1994
Highly Cited
1994
Tc1 transposase of Caenorhabditis elegans is an endonuclease with a bipartite DNA binding domain.
The Tc1 transposon of Caenorhabditis elegans is a member of the Tc1/mariner family of mobile elements. These elements have… 
Highly Cited
1993
Highly Cited
1993
Site-selected insertion of the transposon Tc1 into a Caenorhabditis elegans myosin light chain gene
We used the polymerase chain reaction to detect insertions of the transposon Tc1 into mlc-2, one of two Caenorhabditis elegans… 
Highly Cited
1991
Highly Cited
1991
The origin of footprints of the Tc1 transposon of Caenorhabditis elegans.
Mutations caused by the Tc1 transposon in Caenorhabditis elegans can revert by loss of the element. Usually the transposon leaves… 
Highly Cited
1985
Highly Cited
1985
Hematopoietic factor production by a cell line (TC-1) derived from adherent murine marrow cells.
An adherent cell line, termed TC-1, has been isolated from long-term liquid culture of murine marrow cells by repeated exposure… 
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