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Knowledge and investigation of therapeutic targets (responsible for drug efficacy) and the targeted drugs facilitate target and drug discovery and validation. Therapeutic Target Database (TTD, http://bidd.nus.edu.sg/group/ttd/ttd.asp) has been developed to provide comprehensive information about efficacy targets and the corresponding approved, clinical(More)
A topic propagating in a social network reaches its tipping point if the number of users discussing it in the network exceeds a critical threshold such that a wide cascade on the topic is likely to occur. In this paper, we consider the task of selecting initial seed users of a topic with minimum size so that {\em with a guaranteed probability} the number of(More)
This paper presents a methodology of optimizing power systems demand due to electric vehicle (EV) charging load. Following a brief introduction to the charging characteristics of EV batteries, a statistical model is presented for predicting the EV charging load. The optimization problem is then described, and the solution is provided based on the model. An(More)
A comparative definition for community in networks is proposed, and the corresponding detecting algorithm is given. A community is defined as a set of nodes, which satisfies the requirement that each node's degree inside the community should not be smaller than the node's degree toward any other community. In the algorithm, the attractive force of a(More)
Image quality assessment (IQA) tries to estimate human perception based image visual quality in an objective manner. Existing approaches target this problem with or without reference images. For no-reference image quality assessment, there is no given reference image or any knowledge of the distortion type of the image. Previous approaches measure the image(More)
Sina Weibo, the most popular microblogging service in China, plays a significance role in sharing and exchanging information on local and global level. Actually, part of the information are correlated with some events which may be local ones such as accident, protests or natural disasters to widely ones such as events concerning well-known people or(More)
In cloud data centers, different mapping relationships between virtual machines (VMs) and physical machines (PMs) cause different resource utilization, therefore, how to place VMs on PMs to improve resource utilization and reduce energy consumption is one of the major concerns for cloud providers. The existing VM placement schemes are to optimize physical(More)