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Bupivacaine

Known as: dl-1-Butyl-2',6'-pipecoloxylidide, racemic bupivacaine, 2-Piperidinecarboxamide, 1-butyl-N-(2,6-dimethylphenyl)- 
An amide-type, long-acting local anesthetic. Bupivicaine reversibly binds to specific sodium ion channels in the neuronal membrane, resulting in a… 
National Institutes of Health

Related topics

Related topics

35 relations
2 ML Bupivacaine Hydrochloride 7.5 MG/ML Injection [Marcaine]20 ML Bupivacaine liposome 13.3 MG/ML Injection [Exparel]20 ML Chloroprocaine hydrochloride 30 MG/ML InjectionAmides

Narrower (10)

2',6'-pipecoloxylidide3-hydroxybupivacaine4'-hydroxybupivacaineBupivacain Janapharm

Broader (1)

Local Anesthetics

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Study of the factors affecting the performance of microextraction by packed sorbent (MEPS) using liquid scintillation counter and liquid chromatography-tandem mass spectrometry.
Highly Cited
2002
Highly Cited
2002
Prophylactic ondansetron is effective in the treatment of nausea and vomiting but not on pruritus after cesarean delivery with intrathecal sufentanil-morphine.
Highly Cited
2001
Highly Cited
2001
Long-term intrathecal infusion of drug combinations for chronic back and leg pain.
Highly Cited
2000
Highly Cited
2000
Comparison of hypotensive epidural anaesthesia and spinal anaesthesia on blood loss and coagulation during and after total hip arthroplasty Note
Background: Hypotensive epidural anaesthesia (HEA) is a technique for reducing peroperative blood loss by significantly lowering… 
Review
1997
Review
1997
Malignant ventricular dysrhythmias in a patient with isovaleric acidemia receiving general and local anesthesia for suction lipectomy.
Highly Cited
1991
Highly Cited
1991
Brachial plexus block with bupivacaine: effects of added alpha-adrenergic agonists: comparison between clonidine and epinephrine
The effects of clonidine and epinephrine, administered into the brachial plexus sheath, were evaluated in 60 patients who… 
Highly Cited
1990
Highly Cited
1990
Effects of Oral and Subarachnoid Clonidine on Spinal Anesthesia with Bupivacaine
This study was designed to determine whether clonidine has analgesic properties, decreases the minimum alveolar concentration of… 
Highly Cited
1986
Highly Cited
1986
Epidural Injections of Bupivacaine, Morphine, Fentanyl, Lofentanil, and DADL in Chronically Implanted Rats: A Pharmacologic and Pathologic Study
A new technique of epidural catheterization in rats is described. The pharmacologic characterizations of the model were… 
Highly Cited
1980
Highly Cited
1980
Cardiopulmonary arrest after retrobular block.
Highly Cited
1976
Highly Cited
1976
Neurobehavioral Responses and Drug Concentrations in Newborns after Maternal Epidural Anesthesia with Bupivacaine
The neurobehavioral status of 20 newborn infants was evaluated after two to four hours of life following maternal epidural… 
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