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Bupivacaine

Known as: dl-1-Butyl-2',6'-pipecoloxylidide, racemic bupivacaine, 2-Piperidinecarboxamide, 1-butyl-N-(2,6-dimethylphenyl)- 
An amide-type, long-acting local anesthetic. Bupivicaine reversibly binds to specific sodium ion channels in the neuronal membrane, resulting in a… 
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
BACKGROUND Pain after shoulder surgery is often treated with interscalene nerve blocks. Single-injection blocks are effective… 
Highly Cited
2006
Highly Cited
2006
Background:  The purpose of this study was to compare the onset and duration of sensory and motor block, as well as the… 
Highly Cited
2006
Highly Cited
2006
The patient was a 58-yr-old, 82-kg, 170-cm male who presented for arthroscopic repair of a torn rotator cuff in the right… 
Highly Cited
2003
Highly Cited
2003
Background and Objectives We previously demonstrated in rats that intravenous infusion of a lipid emulsion increases survival in… 
Highly Cited
2002
Highly Cited
2002
AIMS The aim of this study was to compare the cardiovascular effects of levobupivacaine with those of rac-bupivacaine following i… 
Highly Cited
1997
Highly Cited
1997
We have compared the incidence of CNS symptoms and changes in echocardiography and electrophysiology during i.v. infusions of… 
Highly Cited
1995
Highly Cited
1995
Although pain after laparoscopic cholecystectomy is less intense than after open cholecystectomy, some patients still experience… 
Highly Cited
1989
Highly Cited
1989
The acute central nervous and cardiovascular effects of the local anesthetics ropivacaine and bupivacaine were compared in 12… 
Highly Cited
1989
Highly Cited
1989
Addition of fentanyl to bupivacaine administered for spinal anesthesia for cesarean delivery was evaluated in 56 ASA physical…