Buformin

Known as: Imidodicarbonimidic diamide, N-butyl-, 1 Butylbiguanide, Buformina 
An agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity. Buformin is not metabolized and is excreted in the urine… (More)
National Institutes of Health

Papers overview

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2017
2017
BACKGROUND Peanut allergy is common, life-threatening, and without therapeutic options. We evaluated peanut epicutaneous… (More)
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Highly Cited
2014
Highly Cited
2014
The biguanide metformin is widely prescribed for Type II diabetes and has anti-neoplastic activity in laboratory models. Despite… (More)
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2011
2011
BACKGROUND Peanut allergy is a life-threatening condition for which new efficient and safe treatment is expected. We evaluated… (More)
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2008
2008
Measurement of brain tissue oxygen extraction fraction (OEF) in both baseline and functionally activated states can provide… (More)
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Highly Cited
2008
Highly Cited
2008
As a class, the biguanides induce lactic acidosis, a hallmark of mitochondrial impairment. To assess potential mitochondrial… (More)
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2005
2005
BACKGROUND The formation and accumulation of advanced glycation end products (AGE) in various tissues are known to be involved in… (More)
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Highly Cited
2002
Highly Cited
2002
Metformin, a biguanide, is widely used as an oral hypoglycemic agent for the treatment of type 2 diabetes mellitus. The purpose… (More)
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Review
2001
Review
2001
1105 The history of diabetes mellitus is replete with many therapies, nearly all, including insulin, first given without any… (More)
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Highly Cited
1995
Highly Cited
1995
1. The induction of a calcium-independent isoform of nitric oxide (NO) synthase (iNOS) and a subsequent enhanced formation of NO… (More)
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Highly Cited
1984
Highly Cited
1984
The interactions of pentamethylenetetrazole and ten tetrazole analogues with the picrotoxinin site of the benzodiazepine-GABA… (More)
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