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Buformin Hydrochloride

Known as: 1-Butylbiguanide HCl, Imidodicarbonimidic Diamide, N-Butyl-, Hydrochloride, N-Butylbiguanide HCl 
The hydrochloride salt form of buformin, an agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity. Buformin is not… 
National Institutes of Health

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Buformin

Papers overview

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2014
2014
Dodecyl and octyl esters of fluorescein as protonophores and uncouplers of oxidative phosphorylation in mitochondria at submicromolar concentrations.
2013
2013
Rapid identification of illegally added Buformin hydrochloride in health foods by near infrared spectroscopy
OBJECTIVE To adopt the near infrared( NIR) correlation coefficient method for the rapid identification of illegally added… 
2004
2004
Cellular effects of deoxynojirimycin analogues: inhibition of N-linked oligosaccharide processing and generation of free glucosylated oligosaccharides.
In the accompanying paper [Mellor, Neville, Harvey, Platt, Dwek and Butters (2004) Biochem. J. 381, 861-866] we treated HL60… 
Highly Cited
2004
Highly Cited
2004
Human glutathione S-transferase A2 polymorphisms: variant expression, distribution in prostate cancer cases/controls and a novel form.
Variability of expression of the major glutathione S-transferases (GSTs) of liver, GSTA1 and GSTA2, is thought to affect the… 
2001
2001
Hydrogen peroxide and hydroxyl radical involvement in the activation of caspase-3 in chemically induced apoptosis of HL-60 cells
Abstract: Apoptosis of HL-60 cells induced by actinomycin D, H7, or daunorubicin was shown to involve the activation of caspase-3… 
1997
1997
Novel prodrugs of cyanamide that inhibit aldehyde dehydrogenase in vivo.
S-Methylisothiourea (4), when administered to rats followed by a subsequent dose of ethanol, gave rise to a 119-fold increase in… 
1984
1984
Sustained-release formulation of buformin hydrochloride.
Using buformin hydrochloride, a highly water-soluble drug, as a model drug, a sustainedrelease dosage form was developed. Six… 
1978
1978
[Metabolism and excretion of 32P-aminophon in lactating cattle].
P-labelled aminophon, 0,0-di-u-butyl- (1-n-butylaminocyclohexyl) -phosphonate, an agricultural defoliant and siccant, was applied… 
1972
1972
Gas chromatographic behavior of buformin hydrochloride, phenformin hydrochloride and phenylbiguanide. The pyrolytic formation of substituted 2,4,6-triamino-1,3,5-triazines from biguanides.
Highly Cited
1968
Highly Cited
1968
Purification of the alliin lyase of garlic, Allium sativum L.
1. Alliin lyase (EC 4.4.1.4) was purified up to sevenfold from garlic-bulb homogenates. The enzyme was unstable to storage at -10… 
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