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This work studied the buccal absorption of metoprolol in vitro, ex vivo and in vivo as a function of buffered pH at 7.4, 8.5, 9.0… Expand This study is designed, to find out the effect of innate lipid solubility on buccal absorption of basic drugs with similar pka… Expand SummaryThe buccal absorption of procainamide was studied in 4 normal, male volunteers over a pH range of 5–11. In another… Expand Peptides and polypeptides have important pharmacological properties but only a limited number (e.g. insulin, oxytocin… Expand AbstractObjective: The buccal absorption of captopril does not exhibit the classical pH/partition hypothesis, suggesting that… Expand A buccal potential difference (b.p.d.) exists across the mucous membrane of the mouth, which can be made less negative by contact… Expand The buccal absorption of flurbiprofen was studied in normal men to quantify the transport from the oral cavity in humans and to… Expand Buccal absorption of morphine sulphate and morphine‐3‐glucuronide at various buffer pH values (4 to 10) over 5 min has been… Expand The pKa values, RF values, partition coefficients between n‐heptane and phosphate buffer (pH = 7·4), and buccal absorption tests… Expand Buccal absorption tests indicate that loss of drug from the oral cavity cannot be accounted for solely in terms of passive… Expand