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Breast Cancer Type 1 Susceptibility Protein Measurement

Known as: BRCA1, BRCA1 Measurement, Breast Cancer Type 1 Susceptibility Prot 
The determination of the amount of breast cancer type 1 susceptibility protein present in a sample.
National Institutes of Health

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3 relations
BRCA1 protein, humanCDISC SEND Microscopic Findings Test Name TerminologyClinical Data Interchange Standards Consortium Terminology

Papers overview

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Highly Cited
2004
Highly Cited
2004
Estrogen Receptor Status in BRCA1- and BRCA2-Related Breast Cancer
Purpose: BRCA1-related breast cancers are more frequently estrogen receptor (ER) negative than are either BRCA2-related or… 
Review
2003
Review
2003
The multiple nuclear functions of BRCA1: transcription, ubiquitination and DNA repair.
Highly Cited
2001
Highly Cited
2001
The RING Heterodimer BRCA1-BARD1 Is a Ubiquitin Ligase Inactivated by a Breast Cancer-derived Mutation*
BRCA1-BARD1 constitutes a heterodimeric RING finger complex associated through its N-terminal regions. Here we demonstrate that… 
Highly Cited
1998
Highly Cited
1998
BRCA1 physically associates with p53 and stimulates its transcriptional activity
Mutations of the BRCA1 tumor suppressor gene are the most commonly detected alterations in familial breast and ovarian cancer… 
Review
1998
Review
1998
Decision analysis of prophylactic mastectomy and oophorectomy in BRCA1-positive or BRCA2-positive patients.
PURPOSE Young Ashkenazi Jewish women or those from high-risk families who test positive for BRCA1 or BRCA2 mutant genes have a… 
Highly Cited
1998
Highly Cited
1998
The histologic phenotypes of breast carcinoma occurring before age 40 years in women with and without BRCA1 or BRCA2 germline mutations
Women with breast carcinoma diagnosed before age 40 years have a greater prevalence of germline BRCA1 and BRCA2 mutations than… 
Highly Cited
1997
Highly Cited
1997
Decision analysis--effects of prophylactic mastectomy and oophorectomy on life expectancy among women with BRCA1 or BRCA2 mutations.
BACKGROUND Women with BRCA1 or BRCA2 mutations have an increased risk of breast cancer and ovarian cancer. Prophylactic… 
Highly Cited
1996
Highly Cited
1996
Mutations and Polymorphisms in the familial early‐onset breast cancer (BRCA1) gene
Mutations in the familial early‐onset breast cancer gene (BRCA1 ) account for approximately 2–5% of all breast cancer cases… 
Highly Cited
1996
Highly Cited
1996
The Nuclear Localization Sequences of the BRCA1 Protein Interact with the Importin-α Subunit of the Nuclear Transport Signal Receptor*
The BRCA1 gene product is a nuclear phosphoprotein that is aberrantly localized in the cytoplasm of most breast cancer cells. In… 
Highly Cited
1995
Highly Cited
1995
Rapid detection of BRCA1 mutations by the protein truncation test
More than 75% of the reported mutations in the hereditary breast and ovarian cancer gene, BRCA1, result in truncated proteins. We… 
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