Skip to search formSkip to main contentSkip to account menu

Brain Stem Glioblastoma

Known as: Grade IV Astrocytic Neoplasm of Brain Stem, Grade IV Brainstem Astrocytic Neoplasm, Grade IV Astrocytic Neoplasm of the Brainstem 
A malignant, clinically aggressive astrocytic tumor (glioma) localized in the brain stem. -- 2003
National Institutes of Health

Related topics

Related topics

20 relations
AnaplasiaAstrocytesBrainBrain Stem

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Disruption of parallel and converging signaling pathways contributes to the synergistic antitumor effects of simultaneous mTOR and EGFR inhibition in GBM cells.
Elevated epidermal growth factor receptor (EGFR) and mammalian target of rapamycin (mTOR) signaling are known to contribute to… 
Review
2004
Review
2004
A phase I/II trial of single-agent PTK 787/ZK 222584 (PTK/ZK), a novel, oral angiogenesis inhibitor, in patients with recurrent glioblastoma multiforme (GBM).
1512 Background: VEGF-mediated signaling pathways may be critical to GBM neovascularization, and inhibition of VEGF pathways may… 
Highly Cited
2003
Highly Cited
2003
Treatment of Progressive or Recurrent Glioblastoma Multiforme in Adults with Herpes Simplex Virus Thymidine Kinase Gene Vector-Producer Cells Followed by Intravenous Ganciclovir Administration: A…
To determine the safety and evaluate the efficacy of repeated administration of virus-producing cells (GLI 328) containing the… 
Highly Cited
2002
Highly Cited
2002
Immunohistochemical Detection of Nestin in Pediatric Brain Tumors
Nestin is an intermediate filament protein (IFP) expressed in undifferentiated cells during CNS development and in CNS tumors… 
Review
1998
Review
1998
Growth factor-mediated angiogenesis in the malignant progression of glial tumors: a review.
Highly Cited
1996
Highly Cited
1996
Peripheral blood tyrosinase messenger RNA detection and survival in malignant melanoma.
BACKGROUND The most widely accepted criteria for the evaluation of prognosis of malignant melanoma are histopathologic and… 
Highly Cited
1996
Highly Cited
1996
Intrathecal 131I-labeled antitenascin monoclonal antibody 81C6 treatment of patients with leptomeningeal neoplasms or primary brain tumor resection cavities with subarachnoid communication: phase I…
We aimed to determine the maximum tolerated dose (MTD) of 131I-labeled 81C6 in patients with leptomeningeal neoplasms or brain… 
Highly Cited
1995
Highly Cited
1995
Cell cycle-dependent phosphorylation of the retinoblastoma-related protein p130.
The retinoblastoma-related protein p130 is a putative negative regulator of cell proliferation in mammalian cells. In this study… 
Highly Cited
1994
Highly Cited
1994
Clinical phase-I study of Na2B12H11SH (BSH) in patients with malignant glioma as precondition for boron neutron capture therapy (BNCT).
Highly Cited
1992
Highly Cited
1992
Amino Acid Release from Cerebral Cortex in Experimental Acute Liver Failure, Studied by In Vivo Cerebral Cortex Microdialysis
Abstract: Both increased γ‐aminobutyric acid (GABA)‐ergic and decreased glutamatergic neurotransmission have been suggested… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)