Brain Stem Glioblastoma

Known as: Grade IV Astrocytic Neoplasm of Brain Stem, Grade IV Brainstem Astrocytic Neoplasm, Grade IV Astrocytic Neoplasm of the Brainstem 
A malignant, clinically aggressive astrocytic tumor (glioma) localized in the brain stem. -- 2003
National Institutes of Health

Topic mentions per year

Topic mentions per year

1961-2017
05010019612017

Papers overview

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Highly Cited
2010
Highly Cited
2010
Despite the high doses of radiation delivered in the treatment of patients with glioblastoma multiforme (GBM), the tumors… (More)
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Highly Cited
2010
Highly Cited
2010
Reactive astrocytosis develops in many neurologic diseases, including epilepsy. Astrocytotic contributions to pathophysiology are… (More)
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Highly Cited
2009
Highly Cited
2009
Increasing evidence points to a fundamental role for cancer stem cells (CSC) in the initiation and propagation of many tumors. As… (More)
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Highly Cited
2009
Highly Cited
2009
PURPOSE This open-label, prospective, single-arm, phase II study combined erlotinib with radiation therapy (XRT) and temozolomide… (More)
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Highly Cited
2006
Highly Cited
2006
OBJECT An increasing incidence of brain cancer has been reported for the last three decades. In this study of brain cancer… (More)
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Highly Cited
2005
Highly Cited
2005
Glioblastoma multiforme (GBM) is the most common form of malignant glioma, characterized by genetic instability, intratumoral… (More)
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Highly Cited
2004
Highly Cited
2004
Gliomas are the most common primary tumours of the central nervous system, with nearly 15,000 diagnosed annually in the United… (More)
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Highly Cited
2004
Highly Cited
2004
PURPOSE Conventional treatment of glioblastoma multiforme (GBM) cures less than 5% of patients. We investigated the effect of… (More)
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Highly Cited
2002
Highly Cited
2002
Overexpression of the epidermal growth factor receptor (EGFR) has been shown previously to correlate with enhanced malignant… (More)
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Highly Cited
2000
Highly Cited
2000
Deregulation of G1-S transition control in cell cycle is one of the important mechanisms in the development of human tumors… (More)
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