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Six members of the mammalian transient receptor potential (TRP) ion channels respond to varied temperature thresholds. The… Expand Tissue injury generates endogenous factors that heighten our sense of pain by increasing the response of sensory nerve endings to… Expand Natural products afford a window of opportunity to study important biology. If the natural product is used or abused by human… Expand BACKGROUND
Bradykinin is believed to be the main mediator of symptoms in hereditary (HA) and acquired (AA) angio-oedema due to C1… Expand The Ras-related protein Cdc42 plays a role in yeast cell budding and polarity. Two related proteins, Rac1 and RhoA, promote… Expand Shaker A. Mousa and Thomas M. Reilly The DuPont Merck Pharmaceutical Company Cardiovascular Diseases Div., Exp. Station… Expand Nitric oxide (NO) released by vascular endothelial cells accounts for the relaxation of strips of vascular tissue1 and for the… Expand Endothelium-derived relaxing factor (EDRF) is a labile humoral agent which mediates the action of some vasodilators. Nitrovasodi… Expand Abstract : While studying the inactivation of bradykinin, it was noticed that in addition to carboxypeptidase N, a second enzyme… Expand