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Botulinum Toxin Type A

Known as: Clostridium Botulinum Toxin Type A, BoNT/A, Botulinum Toxins, Type A 
An injectable formulation of a neurotoxin derived through the fermentation of the Hall strain of Clostridium botulinum type A with neuromuscular… Expand
National Institutes of Health

Related topics

Related topics

42 relations
Anal FissureBlepharospasmBotulinum Toxin Type A InjectionClostridium botulinum toxin A Ab:PrThr:Pt:Ser:Ord
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Narrower (13)

BotoxDWP450DysportHengli BTX-A
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Broader (3)

Botulinum ToxinsNeuromuscular AgentsNeurotoxins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Regulation of Calcitonin Gene‐Related Peptide Secretion From Trigeminal Nerve Cells by Botulinum Toxin Type A: Implications for Migraine Therapy
Objective.—To determine the effect of botulinum toxin type A on calcitonin gene‐related peptide secretion from cultured… Expand
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Review
2003
Review
2003
Evidence for Antinociceptive Activity of Botulinum Toxin Type A in Pain Management
  • K. Aoki
  • Headache
  • 2003
    • Corpus ID: 36296594
The neurotoxin, botulinum toxin type A, has been used successfully, in some patients, as an analgesic for myofascial pain… Expand
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Highly Cited
2002
Highly Cited
2002
A multicenter, double-blind, randomized, placebo-controlled study of the efficacy and safety of botulinum toxin type A in the treatment of glabellar lines.
BACKGROUND Botulinum toxin type A (BTX-A) is widely used for facial esthetics but is incompletely studied. OBJECTIVE This study… Expand
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Highly Cited
2000
Highly Cited
2000
Botulinum Toxin Type A as a Migraine Preventive Treatment
Objective.—To assess the safety and efficacy of botulinum toxin type A (BOTOX; Allergan, Inc) in the prevention of migraine. 
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Review
2000
Review
2000
Recommendations for the use of botulinum toxin type A in the management of cerebral palsy.
Botulinum toxin type A (BTX-A) is increasingly being used for the treatment of childhood spasticity, particularly cerebral palsy… Expand
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Highly Cited
1999
Highly Cited
1999
Functional repair of motor endplates after botulinum neurotoxin type A poisoning: biphasic switch of synaptic activity between nerve sprouts and their parent terminals.
Blockade of acetylcholine release by botulinum neurotoxin type A at the neuromuscular junction induces the formation of an… Expand
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Highly Cited
1998
Highly Cited
1998
Crystal structure of botulinum neurotoxin type A and implications for toxicity
Botulinum neurotoxin type A (BoNT/A) is the potent disease agent in botulism, a potential biological weapon and an effective… Expand
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Highly Cited
1996
Highly Cited
1996
Botulinum toxin type A in the treatment of upper extremity spasticity
Spasticity is a disorder of excess muscle tone associated with CNS disease. We hypothesized that botulinum toxin, a neuromuscular… Expand
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Highly Cited
1993
Highly Cited
1993
Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25
NEUROTRANSMITTER release is potently blocked by a group of structurally related toxin proteins produced by Clostridium botulinum1… Expand
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Review
1991
Review
1991
Therapeutic uses of botulinum toxin.
BOTULISM had been recognized by the 18th century, but the observation that a toxin produced by an anaerobic organism might be… Expand
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