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Botulinum Toxin Type A

Known as: Clostridium Botulinum Toxin Type A, BoNT/A, Botulinum Toxins, Type A 
An injectable formulation of a neurotoxin derived through the fermentation of the Hall strain of Clostridium botulinum type A with neuromuscular… 
National Institutes of Health

Related topics

Related topics

42 relations
Anal FissureBlepharospasmBotulinum Toxin Type A InjectionClostridium botulinum toxin A Ab:PrThr:Pt:Ser:Ord

Narrower (13)

BotoxDWP450DysportHengli BTX-A

Broader (3)

Botulinum ToxinsNeuromuscular AgentsNeurotoxins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Treatment outcomes and resource use of patients with neurogenic detrusor overactivity receiving botulinum toxin A (BOTOX®) therapy in Germany
PurposeTo evaluate treatment outcomes and resource consumption of patients with neurogenic detrusor overactivity (NDO) before and… 
Highly Cited
2009
Highly Cited
2009
Lab-on-a-chip for botulinum neurotoxin a (BoNT-A) activity analysis.
A Lab-on-a-chip (LOC) was designed, fabricated and tested for the in vitro detection of botulinum neurotoxin serotype A (BoNT-A… 
Highly Cited
1993
Highly Cited
1993
Direct visualization of botulinum neurotoxin-induced channels in phospholipid vesicles
THE seven botulinum neurotoxin (NT) serotypes produced by strains of Clostridium botulinum inhibit neurotransmitter release from… 
Highly Cited
1990
Highly Cited
1990
The complete amino acid sequence of the Clostridium botulinum type-E neurotoxin, derived by nucleotide-sequence analysis of the encoding gene.
The entire structural gene of the Clostridium botulinum NCTC 11219 type-E neurotoxin (BoNT/E) has been cloned as five overlapping… 
Highly Cited
1990
Highly Cited
1990
The complete amino acid sequence of the Clostridium botulinum type A neurotoxin, deduced by nucleotide sequence analysis of the encoding gene.
A 26-mer oligonucleotide probe was synthesized (based on the determined amino acid sequence of the N-terminus of the Clostridium… 
Highly Cited
1987
Highly Cited
1987
Botulinum toxin A blocks glutamate exocytosis from guinea-pig cerebral cortical synaptosomes.
The exocytotic release of L-glutamate from guinea-pig cerebral cortical synaptosomes can be extensively inhibited by… 
Highly Cited
1985
Highly Cited
1985
Inhibition of exocytosis in bovine adrenal medullary cells by botulinum toxin type D
Botulinum toxins are known to block transmitter release at peripheral cholinergic synapses1, producing muscular weakness and… 
Highly Cited
1984
Highly Cited
1984
Detection of Clostridium botulinum type A toxin by enzyme-linked immunosorbent assay with antibodies produced in immunologically tolerant animals
Immunological tolerance is a state of unresponsiveness to foreign substances (antigens) which can develop in human and animal… 
Highly Cited
1977
Highly Cited
1977
Artificial hybrid protein containing a toxic protein fragment and a cell membrane receptor-binding moiety in a disulfide conjugate. II. Biochemical and biologic properties of diphtheria toxin…
Highly Cited
1975
Highly Cited
1975
Ligand-induced redistribution of lymphocyte membrane ganglioside GM1
Dynamic aspects of the binding of cholera toxin to lymphocyte membranes have been studied. We have shown that the receptor for… 
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