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Botulinum Toxin Type A

Known as: Clostridium Botulinum Toxin Type A, BoNT/A, Botulinum Toxins, Type A 
An injectable formulation of a neurotoxin derived through the fermentation of the Hall strain of Clostridium botulinum type A with neuromuscular… 
National Institutes of Health

Related topics

Related topics

42 relations
Anal FissureBlepharospasmBotulinum Toxin Type A InjectionClostridium botulinum toxin A Ab:PrThr:Pt:Ser:Ord

Narrower (13)

BotoxDWP450DysportHengli BTX-A

Broader (3)

Botulinum ToxinsNeuromuscular AgentsNeurotoxins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Association of botulinum neurotoxin serotypes a and B with synaptic vesicle protein complexes.
Botulinum neurotoxins (BoNTs) elicit flaccid paralysis through cleavage of SNARE proteins within peripheral neurons. There are… 
Highly Cited
2003
Highly Cited
2003
Novel small molecule inhibitors of botulinum neurotoxin A metalloprotease activity.
Highly Cited
1999
Highly Cited
1999
Internalization and Proteolytic Action of Botulinum Toxins in CNS Neurons and Astrocytes
Abstract: Tetanus and botulinum toxins bind and are internalized at the neuromuscular junction. Botulinum neurotoxins (BoNTs… 
Highly Cited
1999
Highly Cited
1999
Effect of botulinum toxin type A on movement-associated rhytides following CO2 laser resurfacing.
BACKGROUND Many patients who undergo CO2 laser resurfacing for correction of rhytides experience recurrence of movement… 
Highly Cited
1993
Highly Cited
1993
Direct visualization of botulinum neurotoxin-induced channels in phospholipid vesicles
THE seven botulinum neurotoxin (NT) serotypes produced by strains of Clostridium botulinum inhibit neurotransmitter release from… 
Highly Cited
1990
Highly Cited
1990
The complete amino acid sequence of the Clostridium botulinum type-E neurotoxin, derived by nucleotide-sequence analysis of the encoding gene.
The entire structural gene of the Clostridium botulinum NCTC 11219 type-E neurotoxin (BoNT/E) has been cloned as five overlapping… 
Highly Cited
1987
Highly Cited
1987
Botulinum toxin A blocks glutamate exocytosis from guinea-pig cerebral cortical synaptosomes.
The exocytotic release of L-glutamate from guinea-pig cerebral cortical synaptosomes can be extensively inhibited by… 
Highly Cited
1985
Highly Cited
1985
Inhibition of exocytosis in bovine adrenal medullary cells by botulinum toxin type D
Botulinum toxins are known to block transmitter release at peripheral cholinergic synapses1, producing muscular weakness and… 
Highly Cited
1984
Highly Cited
1984
Detection of Clostridium botulinum type A toxin by enzyme-linked immunosorbent assay with antibodies produced in immunologically tolerant animals
Immunological tolerance is a state of unresponsiveness to foreign substances (antigens) which can develop in human and animal… 
Highly Cited
1975
Highly Cited
1975
Ligand-induced redistribution of lymphocyte membrane ganglioside GM1
Dynamic aspects of the binding of cholera toxin to lymphocyte membranes have been studied. We have shown that the receptor for… 
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