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Bisindolylmaleimide IX Methanesulfonate

National Institutes of Health

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Ro 31-8220

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2014
2014
Annexin II mediates the neutrophil elastase-stimulated exocytosis of mucin 5ac.
The overexpression and hypersecretion of mucus is a hallmark of several chronic pulmonary inflammatory diseases, including… 
2005
2005
Configurational stability of bisindolylmaleimide cyclophanes: from conformers to the first configurationally stable, atropisomeric bisindolylmaleimides.
The bisindolylmaleimides are selective protein kinase inhibitors that can adopt two limiting diastereomeric (syn and anti… 
2004
2004
Towards configurationally stable bisindolylmaleimide cyclophanes: potential tools for investigating protein kinase function.
The effect of macrocycle size and substitution on the configurational stability of some bisindolylmaleimide cyclophanes was… 
2003
2003
ETA, Mixed ETA/ETB Receptor Antagonists, and Protein Kinase C Inhibitor Prevent Acute Hypoxic Pulmonary Vasoconstriction: Influence of Potassium Channels
The aims of this study were to investigate the effects of a selective ETA (BQ-123), a selective ETB (BQ-788), and a specific… 
1996
1996
Prostacyclin formation elicited by endothelin-1 in rat aorta is mediated via phospholipase D activation and not phospholipase C or A2.
Endothelin-1 (ET-1) is a potent vasoconstrictor peptide that also stimulates production of prostacyclin (PGI2) from arachidonic… 
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