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Ro 31-8220

Known as: Ro31-8220, Ro-31-8220, Ro 318220 
A methanesulfonate salt form, a staurosporine analog that inhibits protein kinase C and induces apoptosis. (NCI)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Terminal differentiation of keratinocytes is a multistep process that requires a coordinated program of gene expression. We aimed… Expand
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Highly Cited
2009
Highly Cited
2009
Lewis lung carcinoma-derived high metastatic A11 cells constitutively overexpress hypoxia-inducible factor (HIF)-1α mRNA compared… Expand
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Highly Cited
2008
Highly Cited
2008
Since protein kinase C (PKC) isoforms are variously implicated in the activation of NF-kappaB, we have investigated the role of… Expand
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Highly Cited
2008
Highly Cited
2008
Second messenger-mediated inside-out activation of integrin alphaIIbbeta3 is a key step in platelet aggregation. We recently… Expand
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Highly Cited
2003
Highly Cited
2003
Inhibition of dephosphorylation of the 20 kDa myosin light chain (MLC(20)) is an important mechanism for the Ca(2+)-induced… Expand
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Highly Cited
2001
Highly Cited
2001
The activity of the endothelial nitric oxide synthase (eNOS) can be regulated independently of an increase in Ca(2+) by the… Expand
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Highly Cited
2000
Highly Cited
2000
The specificities of 28 commercially available compounds reported to be relatively selective inhibitors of particular serine… Expand
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Highly Cited
2000
Highly Cited
2000
Microglia, brain resident macrophages, become activated in brains injured due to trauma, ischemia, or neurodegenerative diseases… Expand
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Highly Cited
1998
Highly Cited
1998
We have identified a novel mitogen- and stress-activated protein kinase (MSK1) that contains two protein kinase domains in a… Expand
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Highly Cited
1996
Highly Cited
1996
The Drosophila gene product Wingless (Wg) is a secreted glycoprotein and a member of the Wnt gene family. Genetic analysis of… Expand
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