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Beta protein
Protein which consists of beta sheets.
National Institutes of Health
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Highly Cited
2009
Highly Cited
2009
γ-Secretase: Successive Tripeptide and Tetrapeptide Release from the Transmembrane Domain of β-Carboxyl Terminal Fragment
Mako Takami
,
Y. Nagashima
,
+4 authors
Y. Ihara
Journal of Neuroscience
2009
Corpus ID: 21184204
Amyloid β protein (Aβ), a pathogenic molecule associated with Alzheimer's disease, is produced by γ-secretase, which cleaves the…
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Highly Cited
2008
Highly Cited
2008
Amyloid β Protein Dimer-Containing Human CSF Disrupts Synaptic Plasticity: Prevention by Systemic Passive Immunization
I. Klyubin
,
V. Betts
,
+11 authors
M. Rowan
Journal of Neuroscience
2008
Corpus ID: 9584326
The current development of immunotherapy for Alzheimer's disease is based on the assumption that human-derived amyloid β protein…
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Highly Cited
2007
Highly Cited
2007
Intake of Sucrose-sweetened Water Induces Insulin Resistance and Exacerbates Memory Deficits and Amyloidosis in a Transgenic Mouse Model of Alzheimer Disease*
Dongfeng Cao
,
Hailin Lu
,
T. Lewis
,
Ling Li
Journal of Biological Chemistry
2007
Corpus ID: 25094418
Compelling evidence indicates that excess consumption of sugar-sweetened beverages plays an important role in the epidemic of…
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Highly Cited
1999
Highly Cited
1999
Designing conditions for in vitro formation of amyloid protofilaments and fibrils.
F. Chiti
,
Paul Webster
,
+4 authors
Christopher M. Dobson
Proceedings of the National Academy of Sciences…
1999
Corpus ID: 22901796
We have been able to convert a small alpha/beta protein, acylphosphatase, from its soluble and native form into insoluble amyloid…
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Highly Cited
1998
Highly Cited
1998
Human recombinant NACP/α-synuclein is aggregated and fibrillated in vitro: Relevance for Lewy body disease
M. Hashimoto
,
L. Hsu
,
+4 authors
E. Masliah
Brain Research
1998
Corpus ID: 40762932
Highly Cited
1997
Highly Cited
1997
Amyloid β Protein Potentiates Ca2+ Influx Through L‐Type Voltage‐Sensitive Ca2+ Channels: A Possible Involvement of Free Radicals
K. Ueda
,
S. Shinohara
,
T. Yagami
,
K. Asakura
,
K. Kawasaki
Journal of Neurochemistry
1997
Corpus ID: 20655981
Abstract: Amyloid β protein (Aβ), the central constituent of senile plaques in Alzheimer's disease (AD) brain, is known to exert…
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Highly Cited
1996
Highly Cited
1996
Evidence that the 42- and 40-amino acid forms of amyloid beta protein are generated from the beta-amyloid precursor protein by different protease activities.
M. Citron
,
T. Diehl
,
G. Gordon
,
A. Biere
,
P. Seubert
,
Dennis J. Selkoe
Proceedings of the National Academy of Sciences…
1996
Corpus ID: 10882477
Cerebral deposition of the amyloid beta protein (A beta) is an early and invariant feature of Alzheimer disease (AD). Whereas the…
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Highly Cited
1989
Highly Cited
1989
Amyloid beta protein enhances the survival of hippocampal neurons in vitro.
J. Whitson
,
D. Selkoe
,
C. Cotman
Science
1989
Corpus ID: 29871686
The beta-amyloid protein is progressively deposited in Alzheimer's disease as vascular amyloid and as the amyloid cores of…
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Highly Cited
1987
Highly Cited
1987
Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus.
R. Tanzi
,
J. Gusella
,
+7 authors
R. Neve
Science
1987
Corpus ID: 10106616
The amyloid beta protein has been identified as an important component of both cerebrovascular amyloid and amyloid plaques of…
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Highly Cited
1984
Highly Cited
1984
Alzheimer's disease and Down's syndrome: sharing of a unique cerebrovascular amyloid fibril protein.
G. Glenner
,
Caine W. Wong
Biochemical and Biophysical Research…
1984
Corpus ID: 5924672
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