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BZL101
Known as:
Apoptosis Inducer BZL101
An orally active aqueous extract derived from the plant Scutellaria barbata with potential antineoplastic activity. Sparing normal cells, apoptosis…
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National Institutes of Health
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Related topics
Related topics
2 relations
Positive Regulation of Apoptosis
Broader (1)
Scutellaria barbata extract
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Current therapeutic role and medicinal potential of Scutellaria barbata in Traditional Chinese Medicine and Western research.
G. Tao
,
Marcy J. Balunas
Journal of Ethnopharmacology
2016
Corpus ID: 206030165
2012
2012
Bezielle Selectively Targets Mitochondria of Cancer Cells to Inhibit Glycolysis and OXPHOS
Vivian Chen
,
R. Staub
,
S. Fong
,
M. Tagliaferri
,
I. Cohen
,
E. Shtivelman
PLoS ONE
2012
Corpus ID: 7794663
Bezielle (BZL101) is a candidate oral drug that has shown promising efficacy and excellent safety in the early phase clinical…
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Review
2010
Review
2010
A phase 1B dose escalation trial of Scutellaria barbata (BZL101) for patients with metastatic breast cancer
Alejandra T. Perez
,
B. Arun
,
+9 authors
C. Shapiro
Breast Cancer Research and Treatment
2010
Corpus ID: 24468810
The purpose of this study was to determine the safety and maximum tolerated dose (MTD) of BZL101 (FDA IND# 59,521), an orally…
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Highly Cited
2010
Highly Cited
2010
BZL101, a phytochemical extract from the Scutellaria barbata plant, disrupts proliferation of human breast and prostate cancer cells through distinct mechanisms dependent on the cancer cell phenotype
C. Marconett
,
T. Morgenstern
,
A. S. San Roman
,
S. Sundar
,
Ankur K. Singhal
,
G. Firestone
Cancer Biology & Therapy
2010
Corpus ID: 22228566
BZL101 is an aqueous extract from the Scutellaria barbata plant shown to have anticancer properties in a variety of human cancers…
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2010
2010
Abstract ES9-2: Understanding the Role of Botanicals in the Management of Breast Cancer
D. Tripathy
2010
Corpus ID: 75706480
Botanical agents have been used for centuries based on empiric observations of salutary effects on a variety of illnesses. A…
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2008
2008
Molecular mechanisms underlying selective cytotoxic activity of BZL101, an extract of Scutellaria barbata, towards breast cancer cells
S. Fong
,
M. Shoemaker
,
+5 authors
E. Shtivelman
Cancer Biology & Therapy
2008
Corpus ID: 13019748
We studied the mechanism of the cytotoxic activity of BZL101, an aqueous extract from the herb Scutellaria barbata D. Don, which…
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2008
2008
A phase I trial of scutellaria barbata (BZL101) for metastatic breast cancer
Alejandra T. Perez
,
H. Shaw
,
+7 authors
D. Tripathy
2008
Corpus ID: 73928857
1099 Background: BZL101 is an aqueous extract from herba Scutellaria Barbata. BZL101 demonstrates in vitro growth inhibitory…
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Highly Cited
2007
Highly Cited
2007
Phase I trial and antitumor effects of BZL101 for patients with advanced breast cancer
H. Rugo
,
E. Shtivelman
,
+9 authors
D. Tripathy
Breast Cancer Research and Treatment
2007
Corpus ID: 25409256
BackgroundBotanical therapies are often used by breast cancer patients yet few clinical trials have evaluated their safety and…
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2007
2007
Molecular mechanisms underlying selective cytotoxic activity of BZL101, an extract of Scutellaria barbata D. Don, towards breast cancer cells
S. Fong
,
M. Shoemaker
,
+7 authors
E. Shtivelman
2007
Corpus ID: 85909870
C59 BZL101, an aqueous extract from the herb Scutellaria barbata D. Don, has completed a phase I clinical trial in a heavily…
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