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BYK 191023

Known as: BYK-191023, BYK191023 
 
National Institutes of Health

Papers overview

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2018
2018
Stimulation of brain nicotinic acetylcholine receptors activates adrenomedullary outflow via brain inducible NO synthase‐mediated S‐nitrosylation
We have demonstrated that i.c.v.‐administered (±)‐epibatidine, a nicotinic ACh receptor (nAChR) agonist, induced secretion of… Expand
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2010
2010
EFFECTS OF A SELECTIVE iNOS INHIBITOR VERSUS NOREPINEPHRINE IN THE TREATMENT OF SEPTIC SHOCK
Inhibition of NOS is not beneficial in septic shock; selective inhibition of the inducible form (iNOS) may represent a better… Expand
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2010
2010
Inhibition of nitric oxide synthase during sepsis: revival because of isoform selectivity?
The excess release of nitric oxide (NO) resulting from the activation of the inducible isoform of the NO synthase (iNOS, NOS2) is… Expand
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2008
2008
BYK191023 (2-[2-(4-Methoxy-pyridin-2-yl)-ethyl]-3H-imidazo[4,5-b]pyridine) Is an NADPH- and Time-Dependent Irreversible Inhibitor of Inducible Nitric-Oxide Synthase
Imidazopyridine derivates were recently shown to be a novel class of selective and arginine-competitive inhibitors of inducible… Expand
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2008
2008
BYK 191023 ( 2-[ 2-( 4-Methoxy-pyridin-2-yl )-ethyl ]-3 H-imidazo [ 4 , 5b ] pyridine ) Is an NADPH-and Time-Dependent Irreversible Inhibitor of Inducible Nitric-Oxide Synthase
Imidazopyridine derivates were recently shown to be a novel class of selective and arginine-competitive inhibitors of inducible… Expand
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2006
2006
The Novel Imidazopyridine 2-[2-(4-Methoxy-pyridin-2-yl)-ethyl]-3H-imidazo[4,5-b]pyridine (BYK191023) Is a Highly Selective Inhibitor of the Inducible Nitric-Oxide Synthase
We have identified imidazopyridine derivatives as a novel class of NO synthase inhibitors with high selectivity for the inducible… Expand
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2006
2006
In Vivo Characterization of the Novel Imidazopyridine BYK191023 [2-[2-(4-Methoxy-pyridin-2-yl)-ethyl]-3H-imidazo[4,5-b]pyridine], a Potent and Highly Selective Inhibitor of Inducible Nitric-Oxide…
Excessive release of nitric oxide from inducible nitric-oxide synthase (iNOS) has been postulated to contribute to pathology in a… Expand
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