BYK 191023

Known as: BYK-191023, BYK191023 
 
National Institutes of Health

Papers overview

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2010
2010
Effects of a selective iNOS inhibitor versus norepinephrine in the treatment of septic shock.
Inhibition of NOS is not beneficial in septic shock; selective inhibition of the inducible form (iNOS) may represent a better… (More)
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2008
2008
BYK 191023 ( 2-[ 2-( 4-Methoxy-pyridin-2-yl )-ethyl ]-3 H-imidazo [ 4 , 5b ] pyridine ) Is an NADPH-and Time-Dependent Irreversible Inhibitor of Inducible Nitric-Oxide Synthase
Imidazopyridine derivates were recently shown to be a novel class of selective and arginine-competitive inhibitors of inducible… (More)
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2008
2008
BYK191023 (2-[2-(4-methoxy-pyridin-2-yl)-ethyl]-3h-imidazo[4,5-b]pyridine) is an NADPH- and time-dependent irreversible inhibitor of inducible nitric-oxide synthase.
Imidazopyridine derivates were recently shown to be a novel class of selective and arginine-competitive inhibitors of inducible… (More)
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2006
2006
O34. Potent and highly selective inhibition of the inducible nitric oxide synthase in vitro and in vivo by the novel imidazopyridine BYK191023
 
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2006
2006
Potent and highly selective inhibition of the inducible nitric oxide synthase by BYK191023
 
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2005
2005
The novel imidazopyridine 2-[2-(4-methoxy-pyridin-2-yl)-ethyl]-3H-imidazo[4,5-b]pyridine (BYK191023) is a highly selective inhibitor of the inducible nitric-oxide synthase.
We have identified imidazopyridine derivatives as a novel class of NO synthase inhibitors with high selectivity for the inducible… (More)
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2005
2005
In vivo characterization of the novel imidazopyridine BYK191023 [2-[2-(4-methoxy-pyridin-2-yl)-ethyl]-3H-imidazo[4,5-b]pyridine], a potent and highly selective inhibitor of inducible nitric-oxide…
Excessive release of nitric oxide from inducible nitric-oxide synthase (iNOS) has been postulated to contribute to pathology in a… (More)
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