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BYK 191023

Known as: BYK-191023, BYK191023 
National Institutes of Health

Papers overview

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2018
2018
Stimulation of brain nicotinic acetylcholine receptors activates adrenomedullary outflow via brain inducible NO synthase‐mediated S‐nitrosylation
We have demonstrated that i.c.v.‐administered (±)‐epibatidine, a nicotinic ACh receptor (nAChR) agonist, induced secretion of… 
2010
2010
EFFECTS OF A SELECTIVE iNOS INHIBITOR VERSUS NOREPINEPHRINE IN THE TREATMENT OF SEPTIC SHOCK
Inhibition of NOS is not beneficial in septic shock; selective inhibition of the inducible form (iNOS) may represent a better… 
2010
2010
Inhibition of nitric oxide synthase during sepsis: revival because of isoform selectivity?
The excess release of nitric oxide (NO) resulting from the activation of the inducible isoform of the NO synthase (iNOS, NOS2) is… 
2008
2008
BYK191023 (2-[2-(4-Methoxy-pyridin-2-yl)-ethyl]-3H-imidazo[4,5-b]pyridine) Is an NADPH- and Time-Dependent Irreversible Inhibitor of Inducible Nitric-Oxide Synthase
Imidazopyridine derivates were recently shown to be a novel class of selective and arginine-competitive inhibitors of inducible… 
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2008
2008
BYK 191023 ( 2-[ 2-( 4-Methoxy-pyridin-2-yl )-ethyl ]-3 H-imidazo [ 4 , 5b ] pyridine ) Is an NADPH-and Time-Dependent Irreversible Inhibitor of Inducible Nitric-Oxide Synthase
Imidazopyridine derivates were recently shown to be a novel class of selective and arginine-competitive inhibitors of inducible… 
  • table 1
  • figure 3
  • figure 2
  • figure 4
  • figure 5
2006
2006
The Novel Imidazopyridine 2-[2-(4-Methoxy-pyridin-2-yl)-ethyl]-3H-imidazo[4,5-b]pyridine (BYK191023) Is a Highly Selective Inhibitor of the Inducible Nitric-Oxide Synthase
We have identified imidazopyridine derivatives as a novel class of NO synthase inhibitors with high selectivity for the inducible… 
  • table 1
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  • table 2
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2006
2006
In Vivo Characterization of the Novel Imidazopyridine BYK191023 [2-[2-(4-Methoxy-pyridin-2-yl)-ethyl]-3H-imidazo[4,5-b]pyridine], a Potent and Highly Selective Inhibitor of Inducible Nitric-Oxide…
Excessive release of nitric oxide from inducible nitric-oxide synthase (iNOS) has been postulated to contribute to pathology in a… 
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