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BX795

National Institutes of Health

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Related topics

2 relations

Broader (2)

PyrimidinesThiophenes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
In Vitro and In Vivo Activity, Tolerability, and Mechanism of Action of BX795 as an Antiviral against Herpes Simplex Virus 2 Genital Infection
Herpes simplex virus type 2 (HSV-2) causes recurrent lesions in the anogenital area that may be transmitted through sexual… 
2020
2020
Infectious bronchitis virus inhibits activation of the TLR7 pathway, but not the TLR3 pathway
Various strains of infectious bronchitis virus (IBV) cause different forms of infectious bronchitis with different clinical signs… 
2018
2018
The cardenolide ouabain suppresses coronaviral replication via augmenting a Na+/K+-ATPase-dependent PI3K_PDK1 axis signaling
2017
2017
Brief Report: Blockade of TANK‐Binding Kinase 1/IKKɛ Inhibits Mutant Stimulator of Interferon Genes (STING)–Mediated Inflammatory Responses in Human Peripheral Blood Mononuclear Cells
Gain‐of‐function mutations in TMEM173, encoding the stimulator of interferon (IFN) genes (STING) protein, underlie a novel type I… 
2016
2016
Innate immune responses in human hepatocyte-derived cell lines alter genotype 1 hepatitis E virus replication efficiencies
Hepatitis E virus (HEV) is a significant health problem in developing countries causing sporadic and epidemic forms of acute… 
2015
2015
Fatty acid synthesis and NLRP3-inflammasome
Fatty acid synthesis is an important process of the lipogenesis [1]. Fatty acid synthesis is tightly regulated by key enzymes… 
Highly Cited
2014
Highly Cited
2014
TLR3 and MDA5 signalling, although not expression, is impaired in asthmatic epithelial cells in response to rhinovirus infection.
Rhinoviruses (RV) are the most common acute triggers of asthma, and airway epithelial cells are the primary site of infection… 
Highly Cited
2013
Highly Cited
2013
PDK1 selectively phosphorylates Thr(308) on Akt and contributes to human platelet functional responses
Summary 3-phosphoinositide-dependent protein kinase 1 (PDK1), a member of the protein A,G and C (AGC) family of proteins, is a… 
2013
2013
Interferon regulatory factor 3 activation mediates viral stimulus-induced bronchial production of thymic stromal lymphopoietin.
2012
2012
Synthesis and structure-activity relationships of a novel series of pyrimidines as potent inhibitors of TBK1/IKKε kinases.
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