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The platelet-activating factor (PAF) antagonist BN-50739 can suppress certain cardiac arrhythmias. PAF is released from ischaemic… Expand Abstract: The Pulsinelli‐Brierley four‐vessel occlusion model was used to study the consequences of hyperglycemic ischemia and… Expand We investigated the mechanism of the hypotensive effect of Sar-[D-Phe8]des-Arg9-bradykinin (BK) in lipopolysaccharide-treated… Expand Abstract: Recent evidence suggests that platelet‐activating factor plays a role in ischemia‐induced neural injury. The Pulsinelli… Expand Anesthetized rats were subjected to coronary artery ligation (CAL) for 72 h and infarct size was measured macroscopically using… Expand Interleukin-2 was recently shown to cause acute lung injury characterized by microvascular permeability defect, interstitial… Expand STUDY OBJECTIVE
The aim was to investigate the role of platelet activating factor (PAF) in myocardial ischaemia by using BN 50739… Expand Platelet-activating factor (PAF) has been demonstrated in the circulation and organs of animals exposed to gram negative… Expand BN 50739, a new PAF receptor antagonist, was tested in vitro and in vivo for its capacity to block PAF, endotoxin and recombinant… Expand The effect of a new PAF antagonist BN 50739 was studied on PAF-induced [3H]-serotonin release from washed rabbit platelets in… Expand