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BMS345541

Known as: BMS-345541 
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Mineral trioxide aggregate promotes the odonto/osteogenic differentiation and dentinogenesis of stem cells from apical papilla via nuclear factor kappa B signaling pathway.
2010
2010
In CD28‐costimulated human naïve CD4+ T cells, I‐κB kinase controls the expression of cell cycle regulatory proteins via interleukin‐2‐independent mechanisms
Stimulation of naïve CD4+ T cells through engagement of the T‐cell receptor (TCR) and the CD28 co‐receptor initiates cell… 
2010
2010
Possible involvements of nuclear factor-kappa B and activator protein-1 in the tumor necrosis factor-alpha-induced upregulation of matrix metalloproteinase-12 in human alveolar epithelial A549 cell…
Matrix metalloproteinase-12 (MMP-12) has been suggested to play an important role in airway inflammatory diseases. Tumor necrosis… 
2009
2009
Periodic, Partial Inhibition of IκB Kinase β-Mediated Signaling Yields Therapeutic Benefit in Preclinical Models of Rheumatoid Arthritis
We have previously shown that inhibitors of IκB kinase β (IKKβ), including 4(2′-aminoethyl)amino-1,8-dimethylimidazo(1,2-a… 
2009
2009
The protein kinase C agonist PEP005 increases NF‐κB expression, induces differentiation and increases constitutive chemokine release by primary acute myeloid leukaemia cells
Acute myeloid leukaemia (AML) cells show constitutive release of several chemokines that occurs in three major clusters: (I… 
2009
2009
Molecular determinants of melanoma malignancy: selecting targets for improved efficacy of chemotherapy
The BRAFV600E mutation is common in human melanoma. This mutation enhances IκB kinase (IKK)/nuclear factor-κB (NF-κB) and… 
2007
2007
Synthesis and biological evaluation of 4-amino derivatives of benzimidazoquinoxaline, benzimidazoquinoline, and benzopyrazoloquinazoline as potent IKK inhibitors.
2007
2007
The IKK Inhibitor BMS-345541 Affects Multiple Mitotic Cell Cycle Transitions
The IκB kinase (IKK) complex controls processes such as inflammation, immune responses, cell survival and the proliferation of… 
Highly Cited
2003
Highly Cited
2003
An inhibitor of IκB kinase, BMS-345541, blocks endothelial cell adhesion molecule expression and reduces the severity of dextran sulfate sodium-induced colitis in mice
AbstractObjective:Inflammatory bowel diseases such as ulcerative colitis and Crohn’s disease are characterized by chronic… 
2003
2003
An inhibitor of IkappaB kinase, BMS-345541, blocks endothelial cell adhesion molecule expression and reduces the severity of dextran sulfate sodium-induced colitis in mice.
OBJECTIVE Inflammatory bowel diseases such as ulcerative colitis and Crohn's disease are characterized by chronic relapsing… 
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