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BMS-791325

Known as: NS5B Polymerase Inhibitor BMS-791325 
A non-nucleoside, polymerase inhibitor of the hepatitis C virus (HCV) nonstructural protein 5B (NS5B), a RNA-dependent RNA polymerase, with potential… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Patients with HCV Genotype-1 who have Failed a Direct-Acting Antiviral Regimen: Virological Characteristics and Efficacy of Retreatment
Background This real-world clinical setting study characterized the virological patterns in genotype-1 patients failing… 
2018
2018
The global origins of resistance-associated variants in the non-structural proteins 5A and 5B of the hepatitis C virus
Abstract New, costly, fast acting, therapies targeting the non-structural proteins 5A and 5B (NS5A and NS5B) regions of the… 
2018
2018
HCV Genotype-3h, a Difficult-to-Diagnose Sub-Genotype in the DAA Era
Background No data are available on the clinical presentation and virological pattern in the case of failure of interferon (IFN… 
2016
2016
Natural occurrence of NS5B inhibitor resistance-associated variants in Brazilian patients infected with HCV or HCV and HIV
Resistance-associated variants (RAVs) represent a challenge to the success of new HCV therapies. The aim of this study was to… 
2016
2016
Prevalence and characteristics of naturally occurring sofosbuvir resistance-associated variants in patients with hepatitis C virus genotype 1 b infection
Jun Ito, Goki Suda, Yoshiya Yamamoto, Atsushi Nagasaka, Ken Furuya, Kenichi Kumagai, Hideaki Kikuchi, Takuto Miyagishima, Tomoe… 
2014
2014
A near-full length genotypic assay for HCV1b.
2014
2014
Natural prevalence of hepatitis C virus (HCV) variants resistant to protease and polymerase inhibitors in patients infected with HCV genotype 1 in Tunisia
Hepatitis C virus (HCV) protease inhibitors (PIs) and polymerase inhibitors: nucleos(t)ide inhibitors (NS5B‐NIs) and non‐nucleos… 
2014
2014
Current race in the development of DAAs (direct-acting antivirals) against HCV.
2011
2011
THE HEPATITIS C TREATMENT PIPELINE REPORT
BMS-650032 • BOCEPREVIR • CTS-1027 • DANOPREVIR • GS 9256 GS 9451 • IDX 320 • MK-5172 • TELAPREVIR • TMC435350 • VANIPREVIR VX… 
Highly Cited
2008
Highly Cited
2008
Selection and Characterization of Hepatitis C Virus Replicons Dually Resistant to the Polymerase and Protease Inhibitors HCV-796 and Boceprevir (SCH 503034)
ABSTRACT HCV-796 is a nonnucleoside inhibitor of the hepatitis C virus (HCV) nonstructural protein 5B (NS5B) polymerase, and… 
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