BMPR2 gene

Known as: Bone Morphogenetic Protein Receptor, Type II (Serine/Threonine Kinase) Gene, BMPR3, BONE MORPHOGENETIC PROTEIN RECEPTOR, TYPE II 
This gene is involved in receptor mediated ligand-induced signal transduction that is critical for endochondral bone formation and embryogenesis.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Genetic studies in mice and humans have shown that the transforming growth factor-beta (TGF-beta) type-I receptor activin… (More)
Is this relevant?
Review
2006
Review
2006
Genetic studies in familial pulmonary arterial hypertension (FPAH) have revealed heterozygous germline mutations in the bone… (More)
  • figure 1
  • figure 2
Is this relevant?
Review
2004
Review
2004
Bone morphogenetic proteins (BMPs) are multi-functional growth factors that belong to the transforming growth factor beta… (More)
Is this relevant?
Highly Cited
2002
Highly Cited
2002
BACKGROUND Mutations in the type II receptor for bone morphogenetic protein (BMPR-II), a receptor member of the transforming… (More)
  • figure 1
  • figure 2
  • figure 4
  • figure 3
  • figure 5
Is this relevant?
Highly Cited
2001
Highly Cited
2001
BACKGROUND Mutations in the type II receptor for bone morphogenetic protein (BMPR-II), a receptor member of the transforming… (More)
  • figure 2
  • figure 1
  • figure 3
  • figure 5
  • figure 4
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Primary pulmonary hypertension (PPH), characterized by obstruction of pre-capillary pulmonary arteries, leads to sustained… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Review
1998
Review
1998
Transforming growth factors-beta (TGF-betas), activins, and bone morphogenetic proteins (BMPs) comprise an evolutionarily well… (More)
Is this relevant?
Highly Cited
1996
Highly Cited
1996
To examine the role of BMP signaling during limb pattern formation, we isolated chicken cDNAs encoding type I (BRK-1 and BRK-2… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • table 1
Is this relevant?
Highly Cited
1995
Highly Cited
1995
Bone morphogenic proteins (BMPs) are universal regulators of animal development. We report the identification and cloning of the… (More)
Is this relevant?
Highly Cited
1995
Highly Cited
1995
Bone morphogenetic proteins (BMPs) are members of the transforming growth factor beta superfamily. Several members of this family… (More)
Is this relevant?