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BLZ 945

Known as: BLZ-945, BLZ945 
National Institutes of Health

Papers overview

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Highly Cited
2019
Highly Cited
2019
Target delivery selective CSF-1R inhibitor to tumor-associated macrophages via erythrocyte-cancer cell hybrid membrane camouflaged pH-responsive copolymer micelle for cancer immunotherapy.
2019
2019
Multicellular gene network analysis identifies a macrophage-related gene signature predictive of therapeutic response and prognosis of gliomas
The tumor-associated microenvironment plays important roles in tumor progression and drug resistance. However, systematic… 
Highly Cited
2018
Highly Cited
2018
Brain region-specific enhancement of remyelination and prevention of demyelination by the CSF1R kinase inhibitor BLZ945
Multiple sclerosis (MS) is a chronic inflammatory disease affecting the central nervous system (CNS). While multiple effective… 
2018
2018
Microglial modulation through colony‐stimulating factor‐1 receptor inhibition attenuates demyelination
Multiple sclerosis (MS) is one of the most common causes of progressive disability affecting young people with very few… 
2018
2018
CSF-1/CSF-1R axis is associated with epithelial/mesenchymal hybrid phenotype in epithelial-like inflammatory breast cancer
Inflammatory breast cancer (IBC) is a rare subtype of breast cancer, accounting for 8–10% of breast cancer-associated deaths in… 
2018
2018
Colony stimulating factor 1 receptor blockade improves the efficacy of chemotherapy against human neuroblastoma in the absence of T lymphocytes
Tumor‐associated macrophages can promote growth of cancers. In neuroblastoma, tumor‐associated macrophages have greater frequency… 
Highly Cited
2016
Highly Cited
2016
Targeting Suppressive Myeloid Cells Potentiates Checkpoint Inhibitors to Control Spontaneous Neuroblastoma
Purpose: Neuroblastoma is the most common extracranial solid cancer type in childhood, and high-risk patients have poor prognosis… 
2016
2016
Regulation of myeloid cells by activated T cells determines the efficacy of PD-1 blockade
ABSTRACT Removal of immuno-suppression has been reported to enhance antitumor immunity primed by checkpoint inhibitors. Although… 
2015
2015
Risk Factors for the Failure of Spinal Burst Fractures Treated Conservatively According to the Thoracolumbar Injury Classification and Severity Score (TLICS): A Retrospective Cohort Trial
Background The management of thoracolumbar (TL) burst fractures is still controversial. The thoracolumbar injury classification… 
Highly Cited
1960
Highly Cited
1960
Structure of the adenylcobamide coenzyme: degradation by cyanide, acid, and light.
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