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BIBN 4096BS

Known as: BIBN4096BS 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

PiperazinesQuinazolines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Mapping the CGRP receptor ligand binding domain: tryptophan-84 of RAMP1 is critical for agonist and antagonist binding.
2005
2005
The role of CGRP and nicotinic receptors in centrally evoked facial blood flow changes
2004
2004
The calcitonin gene‐related peptide (CGRP) receptor antagonist BIBN4096BS blocks CGRP and adrenomedullin vasoactive responses in the microvasculature
Calcitonin gene‐related peptide (CGRP) is a potent microvascular dilator neuropeptide that is considered to play an essential… 
2003
2003
Adrenomedullin receptor binding sites in rat brain and peripheral tissues.
Highly Cited
2003
Highly Cited
2003
Effects of the CGRP receptor antagonist BIBN4096BS on capsaicin‐induced carotid haemodynamic changes in anaesthetised pigs
Calcitonin gene‐related peptide (CGRP), a potent vasodilator released from capsaicin‐sensitive trigeminal sensory nerves, seems… 
Highly Cited
2002
Highly Cited
2002
Efficacy of the non-peptide CGRP receptor antagonist BIBN4096BS in blocking CGRP-induced dilations in human and bovine cerebral arteries: potential implications in acute migraine treatment
Highly Cited
2002
Highly Cited
2002
BIBN4096BS is a potent competitive antagonist of the relaxant effects of α‐CGRP on human temporal artery: comparison with CGRP(8‐37)
Release of CGRP during migraine may produce harmful dilatation of cranial arteries, thereby possibly causing pain. We have… 
Review
2001
Review
2001
Migraine and beyond: cardiovascular therapeutic potential for CGRP modulators
CGRP is a potent vasodilator that has been shown to have a physiological and/or pathological role in neurogenic inflammation… 
Review
2001
Review
2001
CGRP receptors: beyond the CGRP(1)-CGRP(2) subdivision?
Highly Cited
2000
Highly Cited
2000
Characterisation of calcitonin gene-related peptide receptors in rat atrium and vas deferens: evidence for a [Cys(Et)(2, 7)]hCGRP-preferring receptor.
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