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BI 836845

Known as: IGF Ligand Neutralizing Antibody BI 836845 
A humanized IgG1 insulin-like growth factor (IGF) monoclonal antibody targeting the IGF ligands 1 (IGF-1) and 2 (IGF-2), with potential… Expand
National Institutes of Health

Papers overview

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2017
2017
Porcine reproductive and respiratory syndrome (PRRS) is one of the most economically significant viral diseases facing the global… Expand
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2016
2016
Natural Killer (NK) cells, a critical component of the immune response to viral infection, recognize and destroy cells with… Expand
2016
2016
530Background: BI 836845, an IGF ligand-neutralizing antibody, binds IGF-1 and IGF-2, inhibits growth-promoting signaling and… Expand
2014
2014
IGF-1 and IGF-2 are potent mitogens acting through the IGF-1 receptor (IGF-1R). The importance of the IGF system in neoplasia has… Expand
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2014
2014
2617 Background: The IGF signaling pathway has an important role in neoplasia and is associated with cancer progression… Expand
Highly Cited
2013
Highly Cited
2013
Insulin-like growth factor (IGF) signaling is thought to play a role in the development and progression of multiple cancer types… Expand
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2013
2013
Porcine reproductive and respiratory syndrome (PRRS) is one of the most economically significant viral diseases facing the global… Expand
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2004
2004
Interleukin-4 (IL-4), a lymphokine produced mainly by activated T cells and mast cells, is a key regulatory molecule in T-helper… Expand
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1996
1996
Molecular dynamic (MD) simulations of the anticodon hairpin of tRNA(Asp) and of the full tRNA, both in a solvent bath with… Expand
Highly Cited
1995
Highly Cited
1995
In order to study the antigenic structure of the G protein of VHSV, we produced several anti-G monoclonal antibodies (MAbs) and… Expand