E. Westhof

Publications595
h-index94
Citations32,214
Highly Influential Citations1,355
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Genome evolution in yeasts
Identifying the mechanisms of eukaryotic genome evolution by comparative genomics is often complicated by the multiplicity of events that have taken place throughout the history of individual… Expand
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Modelling of the three-dimensional architecture of group I catalytic introns based on comparative sequence analysis.
Alignment of the 87 available sequences of group I self-splicing introns reveals numerous instances of covariation between distant sites. Some of these covariations cannot be ascribed to historical… Expand
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Single Processing Center Models for Human Dicer and Bacterial RNase III
Dicer is a multidomain ribonuclease that processes double-stranded RNAs (dsRNAs) to 21 nt small interfering RNAs (siRNAs) during RNA interference, and excises microRNAs from precursor hairpins. Dicer… Expand
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Geometric nomenclature and classification of RNA base pairs.
Non-Watson-Crick base pairs mediate specific interactions responsible for RNA-RNA self-assembly and RNA-protein recognition. An unambiguous and descriptive nomenclature with well-defined and… Expand
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The non-Watson-Crick base pairs and their associated isostericity matrices.
RNA molecules exhibit complex structures in which a large fraction of the bases engage in non-Watson-Crick base pairing, forming motifs that mediate long-range RNA-RNA interactions and create binding… Expand
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Exact method for the calculation of pseudorotation parameters P, τm and their errors. A comparison of the Altona–Sundaralingam and Cremer–Pople treatment of puckering of five-membered rings
A comparison of the two methods available for describing the puckering of five-membered rings - the Altona-Sundaralingam (A-S) [Altona & Sundaralingam (1972). J. Am. Chem. Soc. 94, 8205-8212]… Expand
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Tools for the automatic identification and classification of RNA base pairs
TLDR
RNAview automatically identifies and classifies the types of base pairs that are formed in nucleic acid structures by various combinations of the three edges, Watson-Crick, Hoogsteen and the Sugar edge. Expand
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Sequence elements outside the hammerhead ribozyme catalytic core enable intracellular activity
The hammerhead ribozyme (HHRz) is a small, naturally occurring ribozyme that site-specifically cleaves RNA and has long been considered a potentially useful tool for gene silencing. The minimal… Expand
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A standard reference frame for the description of nucleic acid base-pair geometry.
A common point of reference is needed to describe the three-dimensional arrangements of bases and base-pairs in nucleic acid structures. The different standards used in computer programs created for… Expand
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A new understanding of the decoding principle on the ribosome
During protein synthesis, the ribosome accurately selects transfer RNAs (tRNAs) in accordance with the messenger RNA (mRNA) triplet in the decoding centre. tRNA selection is initiated by elongation… Expand
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