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BCX 1812

Known as: BCX-1812, BCX1812 
National Institutes of Health

Papers overview

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2007
2007
A direct link between receptor glycosylation and activation following natural ligand interaction has not been observed. Here, we… Expand
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Highly Cited
2005
Highly Cited
2005
Cyclopentane derivatives, designated as BCX-1812, BCX-1827, BCX-1898, and BCX-1923, were tested in parallel with oseltamivir… Expand
Highly Cited
2003
Highly Cited
2003
A convergent and versatile racemic total synthesis of the anti-influenza agent BCX-1812 (RWJ-270201) was accomplished on the… Expand
Review
2002
Review
2002
The cyclopentane peramivir (BCX-1812, RWJ-270201) is a highly selective inhibitor of influenza A and B virus neuraminidases and a… Expand
Highly Cited
2002
Highly Cited
2002
We previously characterized influenza viruses whose selection in the presence of neuraminidase (NA) inhibitors resulted in a… Expand
Highly Cited
2002
Highly Cited
2002
ABSTRACT A-315675 is a novel, pyrrolidine-based compound that was evaluated in this study for its ability to inhibit A and B… Expand
Highly Cited
2002
Highly Cited
2002
Zanamivir and oseltamivir, specific inhibitors of influenza virus neuraminidase, have significantly different characteristics in… Expand
Highly Cited
2001
Highly Cited
2001
The design and synthesis of novel, orally active, potent, and selective inhibitors of influenza neuraminidase differing… Expand
Review
2001
Review
2001
The influenza virus neuraminidase (NA) is important in the pathogenesis of infection and, thus, is an attractive target for… Expand
Highly Cited
2001
Highly Cited
2001
ABSTRACT We have recently reported an influenza virus neuraminidase inhibitor, RWJ-270201 (BCX-1812), a novel cyclopentane… Expand
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