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BCX 1812

Known as: BCX-1812, BCX1812 
National Institutes of Health

Related topics

Related topics

2 relations
RWJ 270201

Broader (1)

peramivir

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2002
Review
2002
Peramivir (BCX-1812, RWJ-270201): potential new therapy for influenza
The cyclopentane peramivir (BCX-1812, RWJ-270201) is a highly selective inhibitor of influenza A and B virus neuraminidases and a… 
Highly Cited
2002
Highly Cited
2002
Comparison of colorimetric, fluorometric, and visual methods for determining anti-influenza (H1N1 and H3N2) virus activities and toxicities of compounds.
Highly Cited
2002
Highly Cited
2002
Susceptibility of recent Canadian influenza A and B virus isolates to different neuraminidase inhibitors.
Highly Cited
2002
Highly Cited
2002
Structural studies of the resistance of influenza virus neuramindase to inhibitors.
Zanamivir and oseltamivir, specific inhibitors of influenza virus neuraminidase, have significantly different characteristics in… 
Highly Cited
2002
Highly Cited
2002
In Vitro Characterization of A-315675, a Highly Potent Inhibitor of A and B Strain Influenza Virus Neuraminidases and Influenza Virus Replication
ABSTRACT A-315675 is a novel, pyrrolidine-based compound that was evaluated in this study for its ability to inhibit A and B… 
2002
2002
Oral Administration of Cyclopentane Neuraminidase Inhibitors Protects Ferrets against Influenza Virus Infection
ABSTRACT Several cyclopentane inhibitors of influenza virus neuraminidase that have inhibitory activities in tissue culture… 
Highly Cited
2002
Highly Cited
2002
Combination Treatment of Influenza A Virus Infections in Cell Culture and in Mice with the Cyclopentane Neuraminidase Inhibitor RWJ-270201 and Ribavirin
Treatment of virus infections with compounds acting by different mechanisms may lead to more potent effects when these agents are… 
Review
2001
Review
2001
RWJ-270201 (BCX-1812): a novel neuraminidase inhibitor for influenza.
The influenza virus neuraminidase (NA) is important in the pathogenesis of infection and, thus, is an attractive target for… 
Highly Cited
2001
Highly Cited
2001
Comparison of the Anti-Influenza Virus Activity of RWJ-270201 with Those of Oseltamivir and Zanamivir
ABSTRACT We have recently reported an influenza virus neuraminidase inhibitor, RWJ-270201 (BCX-1812), a novel cyclopentane… 
2001
2001
Characterization of an influenza A (H3N2) virus resistant to the cyclopentane neuraminidase inhibitor RWJ-270201.
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