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BCX 1812

Known as: BCX-1812, BCX1812 
 
National Institutes of Health

Papers overview

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2007
2007
A direct link between receptor glycosylation and activation following natural ligand interaction has not been observed. Here, we… Expand
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2003
2003
A convergent and versatile racemic total synthesis of the anti-influenza agent BCX-1812 (RWJ-270201) was accomplished on the… Expand
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2003
2003
Experiments were run to determine the effect of oral gavage treatment with the cyclopentane influenza virus neuraminidase… Expand
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Review
2002
Review
2002
The cyclopentane peramivir (BCX-1812, RWJ-270201) is a highly selective inhibitor of influenza A and B virus neuraminidases and a… Expand
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Highly Cited
2002
Highly Cited
2002
We previously characterized influenza viruses whose selection in the presence of neuraminidase (NA) inhibitors resulted in a… Expand
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2002
2002
Zanamivir and oseltamivir, specific inhibitors of influenza virus neuraminidase, have significantly different characteristics in… Expand
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Highly Cited
2002
Highly Cited
2002
Methods have been developed previously for rapid evaluation of compounds for antiviral activity in 96-well microplates, which… Expand
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Highly Cited
2001
Highly Cited
2001
ABSTRACT We have recently reported an influenza virus neuraminidase inhibitor, RWJ-270201 (BCX-1812), a novel cyclopentane… Expand
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Highly Cited
2001
Highly Cited
2001
The design and synthesis of novel, orally active, potent, and selective inhibitors of influenza neuraminidase differing… Expand
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Review
2001
Review
2001
The influenza virus neuraminidase (NA) is important in the pathogenesis of infection and, thus, is an attractive target for… Expand
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