peramivir

Known as: (1S,2S,3R,4R)-3-((1S)-1-acetylamino-2-ethylbutyl))-4-((aminoiminomethyl)amino-2-hydroxycyclopentanecarboxylic acid, trihydrate, 3-(1'-acetylamino-2'-ethyl)butyl-4-((aminoimino)methyl)amino-2-hydroxycyclopentane-1-carboxylic acid, 3-(1-acetamido-2-ethyl-butyl)-4-guanidino-2-hydroxy-cyclopentane-1-carboxylic acid 
A cyclopentane derivative with activity against influenza A and B viruses. Peramivir is a neuraminidase inhibitor which prevents normal processing of… (More)

Topic mentions per year

Topic mentions per year

2002-2018
0204020022018

Papers overview

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Highly Cited
2013
Highly Cited
2013
BACKGROUND On March 30, a novel influenza A subtype H7N9 virus (A/H7N9) was detected in patients with severe respiratory disease… (More)
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2012
2012
Peramivir (BioCryst Pharmaceuticals) is a novel investigational intravenous neuraminidase inhibitor that exhibits potent… (More)
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2011
2011
Influenza virus infections are known to persist longer in patients with underlying diseases, including respiratory tract diseases… (More)
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2010
2010
Pandemic 2009 H1N1 virus isolates containing the neuraminidase inhibitor resistance mutation H275Y have been reported. We… (More)
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Highly Cited
2009
Highly Cited
2009
The neuraminidase inhibitors (NAIs) are an effective class of antiviral drugs for the treatment of influenza A and B infections… (More)
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Highly Cited
2009
Highly Cited
2009
n engl j med 361;23 nejm.org december 3, 2009 2204 grams; any new public plan would probably function similarly to Medicare with… (More)
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2007
2007
There is a limited information with regard to the neuraminidase (NA) mutations conferring resistance to peramivir and zanamivir… (More)
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2006
2006
In the event of an influenza outbreak, antivirals including the neuraminidase (NA) inhibitors, peramivir, oseltamivir, and… (More)
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2005
2005
OBJECTIVE Oseltamivir is the only oral neuraminidase inhibitor currently available; we determined the tolerability and antiviral… (More)
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2003
2003
The influenza neuraminidase (NA) inhibitors peramivir, oseltamivir, and zanamivir are potent inhibitors of NAs from both… (More)
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