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peramivir

Known as: (1S,2S,3R,4R)-3-((1S)-1-acetylamino-2-ethylbutyl))-4-((aminoiminomethyl)amino-2-hydroxycyclopentanecarboxylic acid, trihydrate, 3-(1'-acetylamino-2'-ethyl)butyl-4-((aminoimino)methyl)amino-2-hydroxycyclopentane-1-carboxylic acid, 3-(1-acetamido-2-ethyl-butyl)-4-guanidino-2-hydroxy-cyclopentane-1-carboxylic acid 
A cyclopentane derivative with activity against influenza A and B viruses. Peramivir is a neuraminidase inhibitor which prevents normal processing of… Expand
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Six influenza A(H1N1)pdm09 viruses were detected in Sapporo, Japan, between November and December 2013. All six viruses possessed… Expand
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Review
2013
Review
2013
Please cite this paper as: McKimm‐Breschkin (2012) Influenza neuraminidase inhibitors: Antiviral action and mechanisms of… Expand
Highly Cited
2011
Highly Cited
2011
Antiviral resistance in influenza may not only develop during treatment but also sometimes transmit widely to replace susceptible… Expand
Highly Cited
2010
Highly Cited
2010
Pandemic 2009 H1N1 virus isolates containing the neuraminidase inhibitor resistance mutation H275Y have been reported. We… Expand
Highly Cited
2010
Highly Cited
2010
To the Editor: Since the outbreak of influenza A (H1N1) virus pandemic, almost 300 cases of infection with an oseltamivir… Expand
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Highly Cited
2010
Highly Cited
2010
To the Editor: A 10-year-old girl with acute lymphoblastic leukemia was transferred to our hospital on August 31. The patient… Expand
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Highly Cited
2009
Highly Cited
2009
On October 23 the FDA issued an Emergency Use Authorization for peramivir for the treatment of suspected or confirmed cases of… Expand
Review
2007
Review
2007
Oseltamivir phosphate is a prodrug of oseltamivir carboxylate, a highly specific inhibitor of influenza virus neuraminidases… Expand
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Highly Cited
2006
Highly Cited
2006
In the event of an influenza outbreak, antivirals including the neuraminidase (NA) inhibitors, peramivir, oseltamivir, and… Expand
Review
2003
Review
2003
  • N. Asano
  • Glycobiology
  • 2003
  • Corpus ID: 23044815
About 40 years have passed since the classical glycosidase inhibitor nojirimycin was discovered from the cultured broth of the… Expand
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