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BCR gene

Known as: BCR, D22S662, ALL 
This gene plays a role in signal transduction.
National Institutes of Health

Related topics

Related topics

8 relations
BCR protein, humanBCR wt AlleleBCRP2 genePhiladelphia Chromosome

Papers overview

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2019
2019
Identification of the Direct Substrates of the ABL Kinase via Kinase Assay Linked Phosphoproteomics with Multiple Drug Treatments.
Ableson tyrosine kinase (ABL) plays essential roles in cell differentiation, division, adhesion, and stress response. However… 
2017
2017
Frequency of p 190 and p 210 BCR-ABL rearrangements and survival in Brazilian adult patients with acute lymphoblastic leukemia
Objective: This study investigated the occurrence of the p190 and p210 breakpoint cluster region-Abelson (BCR-ABL) rearrangements… 
Review
2015
Review
2015
Implications of BCR-ABL 1 kinase domain-mediated resistance in chronic myeloid leukemia
Patients with chronic myeloid leukemia develop resistance to both first-generation and secondgeneration tyrosine kinase… 
2013
2013
MIP-1 / CCL 3-mediated maintenance of leukemia-initiating cells in the initiation process of chronic myeloid leukemia
The Rockefeller University Press $30.00 J. Exp. Med. 2013 Vol. 210 No. 12 2661-2673 www.jem.org/cgi/doi/10.1084/jem.20130112 2661… 
2011
2011
Fibrosis, regeneration, and aging: playing chess with evolution.
In this issue of JASN , Iyoda et al. [1][1] report that administration of nilotinib, a second-generation inhibitor of cellular… 
2000
2000
No evidence for persistence of BCR-ABL-positive cells in patients in molecular remission after conventional allogenic transplantation for chronic myeloid leukemia.
genomic and mRNABCR-ABL using DNA-PCR with patientspecific primers and RT-PCR, respectively. Eight patients became RT-PCR… 
2000
2000
Cladribine as monotherapy or combined with dexamethasone and idarubicin or mitoxantrone in previously treated patients with low-grade lymphoid malignancies.
We compared efficiency and toxicity of cladribine (2-CdA) in monotherapy and in combination with dexamethasone and mitoxantrone… 
1998
1998
A new case of chronic myeloid leukemia (CML) in myeloid blast crisis with an atypical (b3/a3) junction of the BCR/ABL gene
A new case of chronic myeloid leukemia (CML) in myeloid blast crisis with an atypical (b3/a3) junction of the BCR/ABL gene 
1995
1995
Chronic myeloid leukemia, BCR/ABL transcript, response to alpha-interferon and survival. The Italian Cooperative Study Group on Chronic Myeloid Leukemia.
There is increasing evidence for a relationship between specific genomic alterations and the distinctive features of leukemia… 
1992
1992
Minor BCR (m-bcr) rearrangements may appear in major BCR (M-bcr)-positive CML cases.
The chromosome 22 derivative, the Philadelphia (Ph) chromosome, results from the reciprocal translocation t(9;22) (q34;q11). On…