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BCR gene

Known as: BCR, D22S662, ALL 
This gene plays a role in signal transduction.
National Institutes of Health

Related topics

Related topics

8 relations
BCR protein, humanBCR wt AlleleBCRP2 genePhiladelphia Chromosome

Papers overview

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Highly Cited
2006
Highly Cited
2006
BCR–ABL1 induces aberrant splicing of IKAROS and lineage infidelity in pre-B lymphoblastic leukemia cells
Pre-B lymphoblastic leukemia cells carrying a BCR–ABL1 gene rearrangement exhibit an undifferentiated phenotype. Comparing the… 
Highly Cited
2003
Highly Cited
2003
Involvement of Akt kinase in the action of STI571 on chronic myelogenous leukemia cells.
Highly Cited
2001
Highly Cited
2001
A translocation breakpoint cluster disrupts the newly defined 3' end of the SNURF-SNRPN transcription unit on chromosome 15.
Balanced translocations affecting the paternal copy of 15q11--q13 are a rare cause of Prader-Willi syndrome (PWS) or PWS-like… 
Review
1996
Review
1996
Cytogenetics and molecular genetics of carcinomas arising from thyroid epithelial follicular cells
Cytogenetic and molecular analyses of thyroid tumors have indicated that these neoplasms represent a good model for analyzing… 
1995
1995
Translocations and amplification of the BCL2 gene are detected in interphase nuclei of non-Hodgkin's lymphoma by in situ hybridization with yeast artificial chromosome clones.
Translocation of the BCL2 gene in B-cell malignancies carrying t(14;18) and amplification of the BCL2 gene in a cell line (HBL-2… 
Highly Cited
1993
Highly Cited
1993
BCR-ABL gene rearrangement and expression of primitive hematopoietic progenitors in chronic myeloid leukemia.
Chronic myeloid leukemia (CML) is characterized by an initial chronic phase of expanded yet orderly clonal hematopoiesis that is… 
Highly Cited
1993
Highly Cited
1993
Cloning of a breakpoint cluster region at band 3q27 involved in human non‐Hodgkin's lymphoma
In a previous cytogenetic analysis, we showed the recurrence of translocations involving band 3q27 and immunoglobulin gene… 
Highly Cited
1991
Highly Cited
1991
Evidence for regulation of the human ABL tyrosine kinase by a cellular inhibitor.
Phosphotyrosine cannot be detected on normal human ABL protein-tyrosine kinases, but activated oncogenic forms of the human ABL… 
Highly Cited
1991
Highly Cited
1991
A novel human homeobox gene lies at the chromosome 10 breakpoint in lymphoid neoplasias with chromosomal translocation t(10;14).
The translocation t(10;14)(q24;q11) is an acquired change seen in 4% to 7% of T-cell acute lymphoblastic leukemias (T-ALL). We… 
Highly Cited
1989
Highly Cited
1989
Nucleotide sequence of both reciprocal translocation junction regions in a patient with Ph positive acute lymphoblastic leukaemia, with a breakpoint within the first intron of the BCR gene.
Breakpoints on chromosome 22 in the translocation t(9;22) found in Philadelphia positive acute lymphoblastic leukaemia patients… 
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