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Philadelphia Chromosome

Known as: Chromosome, Philadelphia, Ph 1 Chromosomes, Philadelphia Chromosome [Disease/Finding] 
An aberrant form of human CHROMOSOME 22 characterized by translocation of the distal end of chromosome 9 from 9q34, to the long arm of chromosome 22… 
National Institutes of Health

Related topics

Related topics

39 relations
ABL1 geneB Acute Lymphoblastic Leukemia, Philadelphia Chromosome NegativeBCR geneBlast Phase

Papers overview

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Highly Cited
1998
Highly Cited
1998
Philadelphia chromosome positive adult acute lymphoblastic leukemia: characteristics, prognostic factors and treatment outcome.
Philadelphia chromosome positive (Ph+) acute lymphoblastic leukemia (ALL) is an aggressive form of acute leukemia that represents… 
Highly Cited
1994
Highly Cited
1994
DNA replication analysis of FMR1, XIST, and factor 8C loci by FISH shows nontranscribed X-linked genes replicate late.
The relationship between the transcriptional state of a locus and the time when it replicates during DNA synthesis is… 
Highly Cited
1994
Highly Cited
1994
Search for linkage to schizophrenia on the X and Y chromosomes.
Markers for X chromosome loci were used in linkage studies of a large group of small families (n = 126) with at least two… 
Highly Cited
1994
Highly Cited
1994
Loss of mutation at the FMR1 locus through multiple exchanges between maternal X chromosomes.
The mutation observed in the fragile X syndrome, an X-linked inherited disorder causing mental retardation, is almost exclusively… 
Highly Cited
1991
Highly Cited
1991
Selection in blood cells from female carriers of the fragile X syndrome: inverse correlation between age and proportion of active X chromosomes carrying the full mutation.
We have studied the patterns of mutation and X inactivation in female carriers of a fragile X mutation, to try to correlate them… 
Highly Cited
1985
Highly Cited
1985
Karyotypic evolution in Ph-positive chronic myeloid leukemia in relation to management and disease progression.
Highly Cited
1985
Highly Cited
1985
Homologies between X and Y chromosomes detected by DNA probes: localisation and evolution.
We have isolated and characterized DNA probes that detect homologies between the X and Y chromosomes. Clone St25 is derived from… 
Highly Cited
1980
Highly Cited
1980
Genetic activity of X chromosomes in pluripotent female teratocarcinoma cells and their differentiated progeny
Highly Cited
1977
Highly Cited
1977
The Philadelphia Chromosome (Ph1) in Adults Presenting with Acute Leukaemia: a Comparison of Ph1+ and Ph1‐ Patients *
To evaluate the frequency and clinical significance of the Philadelphia chromosome (Ph1) in adult acute leukaemia, bone marrow… 
Highly Cited
1967
Highly Cited
1967
DELAYED ONSET OF REPLICATION OF HUMAN X CHROMOSOMES
A controversy exists as to whether the human X chromosomes, both normal and abnormal, replicating late in the period of DNA… 
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