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BCAR1 gene

Known as: Cas scaffolding protein family member 1, BREAST CANCER ANTIESTROGEN RESISTANCE 1, CRKAS 
This gene plays a role in signal transduction and is involved in cell adhesion, migration and proliferation.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
To extend understanding of the genetic architecture and molecular basis of type 2 diabetes (T2D), we conducted a meta-analysis of… Expand
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Review
2009
Review
2009
Src family kinases (SFKs) have a critical role in cell adhesion, invasion, proliferation, survival, and angiogenesis during tumor… Expand
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Highly Cited
2006
Highly Cited
2006
Genomes of human cancer cells are characterized by numerous chromosomal aberrations of uncertain pathogenetic significance. Here… Expand
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Highly Cited
2006
Highly Cited
2006
Cell motility on extracellular matrices critically depends on matrix rigidity, which affects cell adhesion and formation of focal… Expand
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Highly Cited
2004
Highly Cited
2004
Cell migration is a complex, highly regulated process that involves the continuous formation and disassembly of adhesions… Expand
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Treatment of breast cancer with the antiestrogen tamoxifen is effective in approximately one half of the patients with… Expand
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Highly Cited
1997
Highly Cited
1997
The focal adhesion kinase (FAK), a protein-tyrosine kinase (PTK), associates with integrin receptors and is activated by cell… Expand
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Highly Cited
1997
Highly Cited
1997
A number of pathogenic bacteria utilize type III secretion pathways to translocate virulence proteins into host eukaryotic cells… Expand
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Highly Cited
1997
Highly Cited
1997
p130cas (Cas) is an adapter protein that has an SH3 domain followed by multiple SH2 binding motifs in the substrate domain. It… Expand
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Highly Cited
1996
Highly Cited
1996
The Philadelphia chromosome (Ph) translocation generates a chimeric tyrosine kinase oncogene, BCR/ABL, which causes chronic… Expand
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