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BCAR1 gene

Known as: Cas scaffolding protein family member 1, BREAST CANCER ANTIESTROGEN RESISTANCE 1, CRKAS 
This gene plays a role in signal transduction and is involved in cell adhesion, migration and proliferation.
National Institutes of Health

Related topics

Related topics

10 relations
BCAR1 protein, humanBreast CarcinomaCarcinomaCell Adhesion

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
p130Cas alters the differentiation potential of mammary luminal progenitors by deregulating c‐Kit activity
It has recently been proposed that defective differentiation of mammary luminal progenitors predisposes to basal‐like breast… 
2011
2011
BCAR3/AND-34 can signal independent of complex formation with CAS family members or the presence of p130Cas.
Highly Cited
2010
Highly Cited
2010
p130Cas is an essential transducer element in ErbB2 transformation
The ErbB2 oncogene is often overexpressed in breast tumors and associated with poor clinical outcome. p130Cas represents a nodal… 
2008
2008
Nephrocystin-1 interacts directly with Ack1 and is expressed in human collecting duct.
2007
2007
BCAR1 expression in prostate cancer: Association with 16q23 LOH status, tumor progression and EGFR/KAI1 staining
The 16q23 locus has been recently suggested in both breast and prostate cancer to contain a gene involved in disease progression… 
2004
2004
Cleavage of p130Cas in anoikis
p130Cas is a multifunctional signaling adaptor protein. It integrates and relays signals generated from a variety of… 
2001
2001
Protein phosphatase 2A interacts with the Src kinase substrate p130CAS
In this study, we report that the Src substrate Cas (p130 Crk-associated substrate) associates with protein phosphatase 2A (PP2A… 
Highly Cited
1999
Highly Cited
1999
Urokinase-type plasminogen activator binding to its receptor stimulates tumor cell migration by enhancing integrin-mediated signal transduction.
Urokinase-type plasminogen activator (uPA) and its receptor (uPAR) participate in matrix degradation and cell migration by… 
1997
1997
Detection of distinct pools of the adapter protein p130CAS using a panel of monoclonal antibodies.
Dynamic protein interactions are thought to play an important role in regulating a wide variety of signal transduction pathways… 
1987
1987
Tumorigenicity test of 1,3- and 1,8-dinitropyrene in BALB/c mice.
1,3-Dinitropyrene (DNP) and 1,8-DNP (CAS: 42397-65-9) are very potent mutagens and induce a frameshift-type mutation in the… 
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