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BCAR1 gene

Known as: Cas scaffolding protein family member 1, BREAST CANCER ANTIESTROGEN RESISTANCE 1, CRKAS 
This gene plays a role in signal transduction and is involved in cell adhesion, migration and proliferation.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
To extend understanding of the genetic architecture and molecular basis of type 2 diabetes (T2D), we conducted a meta-analysis of… Expand
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Review
2009
Review
2009
Src family kinases (SFKs) have a critical role in cell adhesion, invasion, proliferation, survival, and angiogenesis during tumor… Expand
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Highly Cited
2006
Highly Cited
2006
Genomes of human cancer cells are characterized by numerous chromosomal aberrations of uncertain pathogenetic significance. Here… Expand
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Highly Cited
2004
Highly Cited
2004
Cell migration is a complex, highly regulated process that involves the continuous formation and disassembly of adhesions… Expand
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Review
2002
Review
2002
  • T. S. Panetti
  • Frontiers in bioscience : a journal and virtual…
  • 2002
  • Corpus ID: 35708933
Integrins are transmembrane receptors that mediate cell attachment to the substrate. At the cytoplasmic surface of the integrin… Expand
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Highly Cited
1998
Highly Cited
1998
p130Cas (Cas), the protein encoded by the Crkas gene (also known as Cas), is an adaptor molecule with a unique structure that… Expand
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Highly Cited
1997
Highly Cited
1997
The focal adhesion kinase (FAK), a protein-tyrosine kinase (PTK), associates with integrin receptors and is activated by cell… Expand
Highly Cited
1997
Highly Cited
1997
A number of pathogenic bacteria utilize type III secretion pathways to translocate virulence proteins into host eukaryotic cells… Expand
Highly Cited
1996
Highly Cited
1996
p130 is a major tyrosine-phosphorylated protein that tightly binds v-Crk in v-crk-transformed cells and v-Src in v-src… Expand
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Highly Cited
1995
Highly Cited
1995
  • T. Polte, S. Hanks
  • Proceedings of the National Academy of Sciences…
  • 1995
  • Corpus ID: 13217571
The focal adhesion kinase (FAK) has been implicated in integrin-mediated signaling events and in the mechanism of cell… Expand