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BCAR1 gene

Known as: Cas scaffolding protein family member 1, BREAST CANCER ANTIESTROGEN RESISTANCE 1, CRKAS 
This gene plays a role in signal transduction and is involved in cell adhesion, migration and proliferation.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
To extend understanding of the genetic architecture and molecular basis of type 2 diabetes (T2D), we conducted a meta-analysis of… 
Review
2009
Review
2009
Src family kinases (SFKs) have a critical role in cell adhesion, invasion, proliferation, survival, and angiogenesis during tumor… 
Highly Cited
2006
Highly Cited
2004
Highly Cited
2004
Cell migration is a complex, highly regulated process that involves the continuous formation and disassembly of adhesions… 
Highly Cited
1998
Highly Cited
1998
p130Cas (Cas), the protein encoded by the Crkas gene (also known as Cas), is an adaptor molecule with a unique structure that… 
Highly Cited
1997
Highly Cited
1997
The focal adhesion kinase (FAK), a protein-tyrosine kinase (PTK), associates with integrin receptors and is activated by cell… 
Highly Cited
1997
Highly Cited
1997
A number of pathogenic bacteria utilize type III secretion pathways to translocate virulence proteins into host eukaryotic cells… 
Highly Cited
1996
Highly Cited
1996
p130 is a major tyrosine-phosphorylated protein that tightly binds v-Crk in v-crk-transformed cells and v-Src in v-src… 
Highly Cited
1996
Highly Cited
1996
Integrin/ligand binding evokes tyrosine phosphorylation of various proteins. We reported previously that a 105 kD protein (pp105… 
Highly Cited
1995
Highly Cited
1995
  • T. PolteS. Hanks
  • Proceedings of the National Academy of Sciences…
  • 1995
  • Corpus ID: 13217571
The focal adhesion kinase (FAK) has been implicated in integrin-mediated signaling events and in the mechanism of cell…