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BAL101553

Known as: Microtubule-targeted Agent BAL101553 
An orally available, highly water-soluble lysine prodrug of the synthetic small molecule BAL27862 with potential antitumor activity. Upon… Expand
National Institutes of Health

Papers overview

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2018
2018
Human glioblastoma (GBM) is a highly aggressive, invasive and hypervascularised malignant brain cancer. Individual circulating… Expand
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2017
2017
TPS2602Background: BAL101553 (prodrug of BAL27862), is a novel TCC that promotes tumor cell death by modulating the spindle… Expand
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2016
2016
Glioblastoma patients have limited treatment options. Cancer stem-like cells (CSLC) contribute to glioblastoma invasiveness and… Expand
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2016
2016
2525Background: BAL101553 (prodrug of BAL27862) is a small molecule TCC that binds microtubules and promotes tumor cell death… Expand
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2015
2015
Background: BAL101553 is a highly soluble prodrug of BAL27862, a novel, small molecule, microtubule (MT)-depolymerizing agent… Expand
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2015
2015
BAL101553 is a highly water soluble prodrug of BAL27862 that arrests tumor cell proliferation and induces cell death in cancer… Expand
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Highly Cited
2014
Highly Cited
2014
Microtubule-targeting agents are widely used for the treatment of cancer and as tool compounds to study the microtubule… Expand
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2013
2013
2566 Background: BAL101553, a pro-drug of the small molecule BAL27862, is a novel microtubule targeting agent (MTA) with… Expand
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2012
2012
Background: Docetaxel is used as first line chemotherapy for metastatic castrate resistant prostate cancer (mCRPC). It has been… Expand
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2010
2010
Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC Background: [BAL27862][1] is a synthetic small… Expand
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