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BAL101553
Known as:
Microtubule-targeted Agent BAL101553
An orally available, highly water-soluble lysine prodrug of the synthetic small molecule BAL27862 with potential antitumor activity. Upon…
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National Institutes of Health
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Related topics
Related topics
4 relations
Broader (2)
Benzimidazoles
Oxadiazoles
Microtubule Process
NCIt Antineoplastic Agent Terminology
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Genetics and Genomics Detection of circulating tumour cell clusters in human glioblastoma
Ilona Krol
,
F. Castro-Giner
,
+14 authors
N. Aceto
2018
Corpus ID: 261290743
Human glioblastoma (GBM) is a highly aggressive, invasive and hypervascularised malignant brain cancer. Individual circulating…
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2016
2016
Phase 1/2a trial of intravenous BAL101553, a novel tumor checkpoint controller (TCC), in advanced solid tumors.
Juanita Lopez
,
T. R. Jeffry Evans
,
+17 authors
R. Kristeleit
2016
Corpus ID: 80457841
2525Background: BAL101553 (prodrug of BAL27862) is a small molecule TCC that binds microtubules and promotes tumor cell death…
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2015
2015
A randomized Phase 2a study to assess pharmacodynamics, antitumor activity and safety of intravenous BAL101553, a novel microtubule inhibitor, at two dose levels in adult patients with selected…
R. Kristeleit
,
A. Smith
,
+17 authors
L. Molife
2015
Corpus ID: 74580962
TPS2611 Background: BAL101553 is the pro-drug of BAL27862, a novel small-molecule microtubule-targeting agent with potent…
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