B43-PAP immunotoxin

Known as: B43 Immunotoxin, B43-PAP, B43-Pokeweed Antiviral Protein Immunotoxin 
A mouse-derived anti-human CD19 monoclonal antibody linked to pokeweed (Phytolacca americana) antiviral protein (PAP) with antileukemic activity. The… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1986-2015
01219862015

Papers overview

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1998
1998
We have compared the antileukemic activity of the investigational biotherapeutic agent B43-PAP to the antileukemic activities of… (More)
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1997
1997
We studied the pharmacokinetic features, immunogenicity, and toxicity of B43-pokeweed antiviral protein (PAP) immunotoxin in 13… (More)
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1997
1997
We evaluated the TXU (anti-CD7)-pokeweed antiviral protein (PAP) immunotoxin in both murine and nonhuman primate models. TXU-PAP… (More)
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1995
1995
Standard immunotoxin production procedures using whole IgG as the MoAb moiety yield a heterogeneous mixture of 180 kDa, 210 kDa… (More)
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1993
1993
Human mixed lineage leukemia cell line RS4;11 with the t(4;11)(q21;q23) translocation causes disseminated and invariably fatal… (More)
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1992
1992
A highly aggressive subclone of the human CALLA+C mu+ pre-B acute lymphoblastic leukemia (ALL) cell line NALM-6 (designated NALM… (More)
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1992
1992
A highly aggressive human CALLA+C mu+ pre-B acute lymphoblastic leukemia (ALL) cell line (NALM-6-UM1) causes disseminated and… (More)
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1992
1992
We show that a highly aggressive subclone of murine BCL-1 B-lineage leukemia expresses a single 2.4-kb transcript hybridizing to… (More)
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1991
1991
We describe a standardized method for the preparation and purification of a potent immunotoxin against B-lineage leukemia… (More)
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1986
1986
We report a novel colony assay for B-lineage progenitor cells in acute lymphoblastic leukemia (ALL). The primary plating… (More)
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