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Azixa

 
National Institutes of Health

Papers overview

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2015
2015
Induction of apoptosis by the activation of caspase 3 makes it a promising target for designing anticancer drugs hence an… Expand
2015
2015
Glioblastoma Multiforme (GBM) is a highly fatal disease and new chemotherapeutic agents are desperately needed to treat GBM… Expand
2015
2015
OBJECTIVE: To establish safety, tolerability and efficacy of Azixa when combined with standard of care therapy (SOC) (RT/TMZ) in… Expand
2014
2014
Two analogues of the discontinued tumor vascular‐disrupting agent verubulin (Azixa®, MPC‐6827, 1) featuring benzo‐1,4‐dioxan‐6‐yl… Expand
2010
2010
MPC-6827 (Azixa) is a small-molecule microtubule-destabilizing agent that binds to the same (or nearby) sites on β-tubulin as… Expand
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2010
2010
As a continuation of our efforts to discover and develop apoptosis inducing N-methyl-4-(4-methoxyanilino)quinazolines as novel… Expand
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2010
2010
8531 Background: MPC-6827 (Azixa) is a microtubule destabilizing agent. This study was designed to establish the safety and… Expand
2010
2010
2095 Background: MPC-6827 (Azixa; 4-arylaminoquinazoline) is a microtubule destabilizing agent that achieves high brain… Expand
2010
2010
MPC-6827 (Azixa) is a small-moleculemicrotubule-destabilizing agent that binds to the same (or nearby) sites on b-tubulin as… Expand
  • figure 1
  • table 1
  • table 2
  • table 3
  • table 4
2009
2009
AACR Annual Meeting-- Apr 18-22, 2009; Denver, CO Purpose: Azixa\#8482; (MPC-6827) (4-arylaminoquinazolines) is a small molecule… Expand