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Azetidinecarboxylic Acid

Known as: Azetidine 2 carboxylic Acid, Acid, Azetidine-2-carboxylic, 2-Azetidinecarboxylic acid 
A proline analog that acts as a stoichiometric replacement of proline. It causes the production of abnormal proteins with impaired biological… 
National Institutes of Health

Related topics

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16 relations

Narrower (9)

2''-hydroxynicotianamine2'-deoxymugineic acid3-hydroxymugineic acidazelnidipine
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Distinct stress conditions result in aggregation of proteins with similar properties
Protein aggregation is the abnormal association of proteins into larger aggregate structures which tend to be insoluble. This… 
Highly Cited
2006
Highly Cited
2006
Up-regulation of the clusterin gene after proteotoxic stress: implication of HSF1-HSF2 heterocomplexes.
Clusterin is a secreted protein chaperone up-regulated in several pathologies, including cancer and neurodegenerative diseases… 
Highly Cited
2004
Highly Cited
2004
Nck-dependent activation of extracellular signal-regulated kinase-1 and regulation of cell survival during endoplasmic reticulum stress.
In response to stress, the endoplasmic reticulum (ER) signaling machinery triggers the inhibition of protein synthesis and up… 
Highly Cited
2002
Highly Cited
2002
Misfolded Proteins Are Competent to Mediate a Subset of the Responses to Heat Shock in Saccharomyces cerevisiae * 210
Cells may sense heat shock via the accumulation of thermally misfolded proteins. To explore this possibility, we determined the… 
Highly Cited
2002
Highly Cited
2002
Proline Residues at the C Terminus of Nascent Chains Induce SsrA Tagging during Translation Termination* 210
The SsrA or tmRNA quality control system relieves ribosome stalling and directs the addition of a degradation tag to the C… 
Highly Cited
1998
Highly Cited
1998
Identification and initial structure-activity relationships of (R)-5-(2-azetidinylmethoxy)-2-chloropyridine (ABT-594), a potent, orally active, non-opiate analgesic agent acting via neuronal…
New members of a previously reported series of 3-pyridyl ether compounds are disclosed as novel, potent analgesic agents acting… 
Highly Cited
1977
Highly Cited
1977
Ammonium and amino acids as regulators of nitrate reductase in corn roots.
When amino acids or ammonia are added to plant systems, the effects on the development of nitrate-dependent nitrate reductase… 
Highly Cited
1975
Highly Cited
1975
Regulation of herpesvirus macromolecular synthesis: sequential transition of polypeptide synthesis requires functional viral polypeptides.
It was previously shown that virus-specific polypeptides made in HEp-2 cells infected with herpes simplex 1 form three groups… 
Highly Cited
1970
Highly Cited
1970
The preparation and properties of some nitrosamino acids.
Highly Cited
1970
Highly Cited
1970
Further evidence on the formation of poliovirus proteins.
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