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Avosentan

Known as: 2-Pyridinesulfonamide, N-(6-methoxy-5-(2-methoxyphenoxy)-2-(4-pyridinyl)-4-pyrimidinyl)-5-methyl-, 5-methylpyridine-2-sulfonic acid (6-methoxy-5-(2-methoxyphenoxy)-2-(pyridin-4-yl)pyrimidin-4-yl)amide 
National Institutes of Health

Papers overview

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2014
2014
The PREDIAN trial investigated the renoprotective effects of pentoxifylline, in addition to renin–angiotensin system blockade, in… 
2010
2010
When Yanagisawa et al. 1 first identified endothelin (ET), a novel polypeptide vasoconstrictor for which numerous other functions… 
2010
2010
Diabetic nephropathy (DN) is the leading cause of end-stage renal disease and affects an estimated 150 million people worldwide… 
2009
2009
OBJECTIVE Avosentan is a potent, selective endothelin A receptor blocker. The pharmacokinetics of avosentan were investigated in… 
2008
2008
OBJECTIVE Avosentan is a potent, selective endothelin A receptor blocker. The effect of food intake on the pharmacokinetics of… 
2007
2007
The present invention relates to a pharmaceutical composition and method of achieving a therapeutic effect including, but not… 
2007
2007
The present invention is allowed (i) SPP100 / aliskiren or a combination thereof and a pharmaceutically acceptable salt thereof… 
2007
2007
1. A pharmaceutical composition comprising (1) SPP100 / aliskiren or a pharmaceutically acceptable salt thereof, (2) SPP301…