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SPP301

Known as: Ro 67-0565 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Avosentan

Papers overview

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2006
2006
Pharmacokinetic interaction between ketoconazole and SPP301 in healthy volunteers.
BACKGROUND SPP301 is a potent and highly selective ETA receptor blocker. The primary aim of the present study was to investigate… 
2005
2005
Multiple-dose pharmacokinetics, pharmacodynamics and tolerability of the oral ET(A) endothelin-receptor antagonist SPP301 in man.
BACKGROUND SPP301 is a competitive antagonist of ET-1 with a high selectivity for the ET(A) receptor. The multiple-dose… 
2004
2004
THE ETA-SELECTIVE ANTAGONIST SPP301 REDUCES PROTEINURIA IN PATIENTS WITH DIABETIC NEPHROPATHY ON TOP OF HIGH-DOSE AT1 RECEPTOR BLOCKADE (ARB): P3.256
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