Autoimmune arthritis
National Institutes of Health
Papers overview
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Recent studies have shown that cellular metabolism plays an important role in regulating immune cell functions. In immune cell…
CD8+ T cells are key players in the body's defence against viral infections and cancer. To date, data on the role of CD8+ T cells…
Synovial fibroblasts (SFs) with aberrant expression of microRNAs (miRNAs) are critical pathogenic regulators in rheumatoid…
In autoimmune diseases, a disturbance of the balance between T helper 17 (Th17) and regulatory T cells (Tregs) is often observed…
Interleukin-17 (IL-17)-producing γδ T (γδ17) cells have been implicated in inflammatory diseases, but the underlying pathogenic…
TGF-β-activated kinase 1 (TAK1 or MAP3K7) is an intracellular hub molecule that regulates both nuclear factor-κB (NF-κB) and…
IntroductionAnti-citrullinated protein antibodies have a diagnostic role in rheumatoid arthritis (RA); however, little is known…
Abstract: Rheumatoid arthritis (RA) is a complex, multifactorial disease with genetic and immunological aspects. Because RA is…
The T cell response to the 65-kD mycobacterial heat-shock protein (Bhsp65) has been implicated in the pathogenesis of autoimmune…
OBJECTIVE
It has been postulated that superantigens might play a role in the human rheumatic diseases, by activation of self…