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Autoimmune Lymphoproliferative Syndrome Type 2B

Known as: Caspase-8 Deficiencies, Caspase-8 Deficiency, Deficiency, Caspase-8 
Autoimmune lymphoproliferative syndrome due to mutations in CASPASE 8 gene.
National Institutes of Health

Related topics

Related topics

9 relations
AsthmaAutosomal recessive inheritanceChronic diarrheaEczema
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Broader (1)

Autoimmune Lymphoproliferative Syndrome

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
Historical (1750–2014) anthropogenic emissions of reactive gases and aerosols from the Community Emissions Data System (CEDS)
Abstract. We present a new data set of annual historical (1750–2014) anthropogenic chemically reactive gases (CO, CH4, NH3, NOx… Expand
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Highly Cited
2011
Highly Cited
2011
Mechanisms of necroptosis in T cells
In caspase 8-deficient mouse T cells, necroptosis occurs via a Ripk3- and Ripk1-dependent pathway independent of autophagy and… Expand
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Review
2007
Review
2007
Mapping Population Distribution in the Urban Environment: The Cadastral-based Expert Dasymetric System (CEDS)
This paper discusses the importance of determining an accurate depiction of total population and specific sub-population… Expand
Highly Cited
2005
Highly Cited
2005
Requirement for caspase-8 in NF-kappaB activation by antigen receptor.
Caspase-8, a proapoptotic protease, has an essential role in lymphocyte activation and protective immunity. We show that caspase… Expand
Highly Cited
2005
Highly Cited
2005
Volatile Anesthetics Induce Caspase-dependent, Mitochondria-mediated Apoptosis in Human T Lymphocytes In Vitro
Background:Volatile anesthetics modulate lymphocyte function during surgery, and this compromises postoperative immune competence… Expand
Highly Cited
2003
Highly Cited
2003
ER stress induces caspase-8 activation, stimulating cytochrome c release and caspase-9 activation.
Excess ER stress induces caspase-12 activation and/or cytochrome c release, causing caspase-9 activation. Little is known about… Expand
Highly Cited
2002
Highly Cited
2002
Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency
Apoptosis is a form of programmed cell death that is controlled by aspartate-specific cysteine proteases called caspases. In the… Expand
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Highly Cited
2002
Highly Cited
2002
IFNγ sensitizes for apoptosis by upregulating caspase-8 expression through the Stat1 pathway
Resistance of tumors to cytotoxic therapy may be due to disrupted apoptosis programs and remains a major obstacle in cancer… Expand
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Highly Cited
2001
Highly Cited
2001
Resistance to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in neuroblastoma cells correlates with a loss of caspase-8 expression.
Disruption of apoptotic pathways may be involved in tumor formation, regression, and treatment resistance of neuroblastoma (NB… Expand
Highly Cited
1995
Highly Cited
1995
Intrinsic epileptogenicity of human dysplastic cortex as suggested by corticography and surgical results
Cortical dysplastic lesions (CDyLs) are often associated with severe partial epilepsies. We describe the electrographic… Expand
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