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Autoimmune Lymphoproliferative Syndrome Type 2B

Known as: Caspase-8 Deficiencies, Caspase-8 Deficiency, Deficiency, Caspase-8 
Autoimmune lymphoproliferative syndrome due to mutations in CASPASE 8 gene.
National Institutes of Health

Papers overview

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Highly Cited
2019
Highly Cited
2019
Caspase-8 is the initiator caspase of extrinsic apoptosis1,2 and inhibits necroptosis mediated by RIPK3 and MLKL. Accordingly… 
Highly Cited
2017
Highly Cited
2017
Abstract. We present a new data set of annual historical (1750–2014) anthropogenic chemically reactive gases (CO, CH4, NH3, NOx… 
Highly Cited
2009
Highly Cited
2009
Expression of enzymatically inactive caspase-8, or deletion of caspase-8 from basal epidermal keratinocytes, triggers chronic… 
Review
2007
Review
2007
This paper discusses the importance of determining an accurate depiction of total population and specific sub-population… 
Highly Cited
2005
Highly Cited
2005
Background:Volatile anesthetics modulate lymphocyte function during surgery, and this compromises postoperative immune competence… 
Highly Cited
2005
Highly Cited
2005
Caspase-8, a proapoptotic protease, has an essential role in lymphocyte activation and protective immunity. We show that caspase… 
Highly Cited
2002
Highly Cited
2002
Apoptosis is a form of programmed cell death that is controlled by aspartate-specific cysteine proteases called caspases. In the… 
Highly Cited
2002
Highly Cited
2002
Resistance of tumors to cytotoxic therapy may be due to disrupted apoptosis programs and remains a major obstacle in cancer… 
Highly Cited
2001
Highly Cited
2001
Disruption of apoptotic pathways may be involved in tumor formation, regression, and treatment resistance of neuroblastoma (NB… 
Highly Cited
1995
Highly Cited
1995
Cortical dysplastic lesions (CDyLs) are often associated with severe partial epilepsies. We describe the electrographic…