Skip to search formSkip to main contentSkip to account menu

Autoimmune Lymphoproliferative Syndrome Type 2B

Known as: Caspase-8 Deficiencies, Caspase-8 Deficiency, Deficiency, Caspase-8 
Autoimmune lymphoproliferative syndrome due to mutations in CASPASE 8 gene.
National Institutes of Health

Related topics

Related topics

9 relations
AsthmaAutosomal recessive inheritanceChronic diarrheaEczema

Broader (1)

Autoimmune Lymphoproliferative Syndrome

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
Regression of apoptosis-resistant colorectal tumors by induction of necroptosis in mice
Cancer cells often acquire capabilities to evade cell death induced by current chemotherapeutic treatment approaches. Caspase-8… 
Highly Cited
2013
Highly Cited
2013
Clinical and molecular characterization of 40 patients with classic Ehlers–Danlos syndrome: identification of 18 COL5A1 and 2 COL5A2 novel mutations
BackgroundClassic Ehlers–Danlos syndrome (cEDS) is a rare autosomal dominant connective tissue disorder that is primarily… 
Highly Cited
2009
Highly Cited
2009
Mapping Urban Risk: Flood Hazards, Race, & Environmental Justice In New York"
Highly Cited
2007
Highly Cited
2007
Role of caspase‐8 in hepatocyte response to infection and injury in mice
Caspase‐8 has been implicated in signaling for apoptotic cell death and for certain nonapoptotic functions. However, knowledge of… 
Highly Cited
2006
Highly Cited
2006
Apoptosome-Independent Activation of the Lysosomal Cell Death Pathway byCaspase-9
ABSTRACT The apoptosome, a heptameric complex of Apaf-1, cytochrome c, and caspase-9, has been considered indispensable for the… 
Highly Cited
2005
Highly Cited
2005
Volatile Anesthetics Induce Caspase-dependent, Mitochondria-mediated Apoptosis in Human T Lymphocytes In Vitro
Background:Volatile anesthetics modulate lymphocyte function during surgery, and this compromises postoperative immune competence… 
Highly Cited
2005
Highly Cited
2005
Requirement for caspase-8 in NF-kappaB activation by antigen receptor.
Caspase-8, a proapoptotic protease, has an essential role in lymphocyte activation and protective immunity. We show that caspase… 
Highly Cited
2002
Highly Cited
2002
IFNγ sensitizes for apoptosis by upregulating caspase-8 expression through the Stat1 pathway
Resistance of tumors to cytotoxic therapy may be due to disrupted apoptosis programs and remains a major obstacle in cancer… 
Highly Cited
2002
Highly Cited
2002
Clustered encouragement designs with individual noncompliance: bayesian inference with randomization, and application to advance directive forms.
In many studies comparing a new 'target treatment' with a control target treatment, the received treatment does not always agree… 
Highly Cited
2001
Highly Cited
2001
Resistance to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in neuroblastoma cells correlates with a loss of caspase-8 expression.
Disruption of apoptotic pathways may be involved in tumor formation, regression, and treatment resistance of neuroblastoma (NB… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)