Autoimmune Lymphoproliferative Syndrome Type 2B

Known as: Caspase-8 Deficiencies, Caspase-8 Deficiency, Deficiency, Caspase-8 
Autoimmune lymphoproliferative syndrome due to mutations in CASPASE 8 gene.
National Institutes of Health

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Highly Cited
2011
Highly Cited
2011
Cell populations are regulated in size by at least two forms of apoptosis. More recently, necroptosis, a parallel, nonapoptotic… (More)
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2009
2009
Expression of enzymatically inactive caspase-8, or deletion of caspase-8 from basal epidermal keratinocytes, triggers chronic… (More)
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2006
2006
Resistance of tumors to cytotoxic therapy remains a major obstacle in cancer treatment and is often caused by defects in… (More)
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2006
2006
The apoptosome, a heptameric complex of Apaf-1, cytochrome c, and caspase-9, has been considered indispensable for the activation… (More)
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Highly Cited
2003
Highly Cited
2003
Excess ER stress induces caspase-12 activation and/or cytochrome c release, causing caspase-9 activation. Little is known about… (More)
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Highly Cited
2002
Highly Cited
2002
Resistance of tumors to cytotoxic therapy may be due to disrupted apoptosis programs and remains a major obstacle in cancer… (More)
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2002
2002
In many studies comparing a new 'target treatment' with a control target treatment, the received treatment does not always agree… (More)
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Highly Cited
2002
Highly Cited
2002
Apoptosis is a form of programmed cell death that is controlled by aspartate-specific cysteine proteases called caspases. In the… (More)
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Highly Cited
2001
Highly Cited
2001
Disruption of apoptotic pathways may be involved in tumor formation, regression, and treatment resistance of neuroblastoma (NB… (More)
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Highly Cited
1995
Highly Cited
1995
Cortical dysplastic lesions (CDyLs) are often associated with severe partial epilepsies. We describe the electrographic… (More)
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