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Aurora Kinases

Known as: Aurora Kinases [Chemical/Ingredient] 
A family of highly conserved serine-threonine kinases that are involved in the regulation of MITOSIS. They are involved in many aspects of cell… 
National Institutes of Health

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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Effects of selective inhibitors of Aurora kinases on anaplastic thyroid carcinoma cell lines.
Aurora kinases are serine/threonine kinases that play an essential role in cell division. Their aberrant expression and/or… 
2014
2014
SAR156497, an exquisitely selective inhibitor of aurora kinases.
The Aurora family of serine/threonine kinases is essential for mitosis. Their crucial role in cell cycle regulation and aberrant… 
2012
2012
Inhibition of Aurora kinases enhances chemosensitivity to temozolomide and causes radiosensitization in glioblastoma cells
BackgroundGlioblastoma remains one of the most devastating human malignancies, and despite therapeutic advances, there are no… 
Review
2011
Review
2011
Targeting aurora kinases in cancer treatment.
The Aurora family of serine/threonine kinases is essential for chromosome alignment, segregation, centrosomal maturation, mitotic… 
Review
2009
Review
2009
Discovery and development of aurora kinase inhibitors as anticancer agents.
The process of cell division or mitosis is highly complex and tightly regulated. During this phase of the cell cycle two… 
Review
2009
Review
2009
Small molecule aurora kinases inhibitors.
Aurora kinases represent one of the emerging targets in oncology drug discovery. These kinases play important role in centrosome… 
Review
2006
Review
2006
Aurora kinase inhibitors: a new class of targeted drugs in cancer.
Aurora kinases (A, B, and C) are essential for spindle assembly, centrosome maturation, chromosomal segregation, and cytokinesis… 
Review
2005
Review
2005
Progress in the development of selective inhibitors of aurora kinases.
Errors in the mitotic process are thought to be one of the principal sources of the genetic instability that hallmarks cancer… 
Review
2005
Review
2005
Progress in the development of selective inhibitors of Aurora kinases.
Errors in the mitotic process are thought to be one of the principal sources of the genetic instability that hallmarks cancer… 
2004
2004
Aurora kinases dawn as cancer drug targets
A new anticancer compound interferes with aurora kinases, regulators of mitosis. We can now hope for the biology of these kinases… 
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