Aurora Kinases

Known as: Aurora Kinases [Chemical/Ingredient] 
A family of highly conserved serine-threonine kinases that are involved in the regulation of MITOSIS. They are involved in many aspects of cell… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2000-2017
05101520002017

Papers overview

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2012
2012
Triple-negative breast cancers (TNBC) have an aggressive phenotype with a relatively high rate of recurrence and poor overall… (More)
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Highly Cited
2009
Highly Cited
2009
Genetic instability and cellular proliferation have been associated with aurora kinase expression in several cancer entities… (More)
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2008
2008
Aurora kinases have emerged as potential targets in cancer therapy, and several drugs are currently undergoing preclinical and… (More)
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2007
2007
The aurora kinases facilitate transit from G2 through cytokinesis and, thus, are targets in cancer therapy. Multiple myeloma (MM… (More)
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2007
2007
Mutations in the kinase domain of Bcr-Abl are the most common cause of resistance to therapy with imatinib in patients with… (More)
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2006
Highly Cited
2006
Most gene expression profiling studies of mesothelioma have been based on relatively small sample numbers, limiting their… (More)
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2005
2005
The Aurora kinase family is a well-characterized serine/threonine protein kinase family that regulates different processes of… (More)
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2005
2005
Modulation of aberrant cell cycle regulation is a potential therapeutic strategy applicable to a wide range of tumor types. JNJ… (More)
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2004
2004
The increasing use of high-throughput and large-scale bioinformatics-based studies has generated a massive amount of data stored… (More)
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2003
2003
Aurora-A kinase, also known as STK15/BTAK kinase, is a member of a serine/threonine kinase superfamily that includes the… (More)
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