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Aurora Kinases

Known as: Aurora Kinases [Chemical/Ingredient] 
A family of highly conserved serine-threonine kinases that are involved in the regulation of MITOSIS. They are involved in many aspects of cell… Expand
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Aurora kinases are serine/threonine kinases essential for the onset and progression of mitosis. Aurora members share a similar… Expand
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Highly Cited
2014
Highly Cited
2014
A number of small-molecule inhibitors of Aurora kinases have been developed and are undergoing clinical trials for anti-cancer… Expand
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Highly Cited
2013
Highly Cited
2013
Oncogene-induced senescence can provide a protective mechanism against tumour progression. However, production of cytokines and… Expand
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Highly Cited
2008
Highly Cited
2008
The demonstration that the small synthetic molecule reversine [2-(4-morpholinoanilino)-N6-cyclohexyladenine] promotes the… Expand
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Highly Cited
2007
Highly Cited
2007
PHA-739358 is a small-molecule 3-aminopyrazole derivative with strong activity against Aurora kinases and cross-reactivities with… Expand
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Highly Cited
2007
Highly Cited
2007
The Aurora kinases play an important role in chromosome alignment, segregation, and cytokinesis during mitosis. Aberrant… Expand
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Highly Cited
2006
Highly Cited
2006
Most gene expression profiling studies of mesothelioma have been based on relatively small sample numbers, limiting their… Expand
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Highly Cited
2005
Highly Cited
2005
Modulation of aberrant cell cycle regulation is a potential therapeutic strategy applicable to a wide range of tumor types. JNJ… Expand
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Review
2004
Review
2004
Aurora kinases representing a novel family of serine/threonine kinases have been identified as key regulators of the mitotic cell… Expand
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Highly Cited
2000
Highly Cited
2000
Phosphorylation of histone H3 at serine 10 occurs during mitosis and meiosis in a wide range of eukaryotes and has been shown to… Expand
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