Aspartate-Semialdehyde Dehydrogenase

Known as: L-Aspartate-4-semialdehyde:NADP+ oxidoreductase (phosphorylating), Aldehyde Dehydrogenase, Semiaspartate, Dehydrogenase, Aspartate-Semialdehyde 
An enzyme that catalyzes the conversion of L-aspartate 4-semialdehyde, orthophosphate, and NADP+ to yield L-4-aspartyl phosphate and NADPH. EC 1.2.1… (More)
National Institutes of Health

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Papers overview

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2012
2012
Molecular docking and enzymatic evaluation to identify selective inhibitors of aspartate semialdehyde dehydrogenase.
Microbes that have gained resistance against antibiotics pose a major emerging threat to human health. New targets must be… (More)
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2012
2012
Structures of ternary complexes of aspartate-semialdehyde dehydrogenase (Rv3708c) from Mycobacterium tuberculosis H37Rv.
Aspartate-semialdehyde dehydrogenase (Asd; ASADH; EC 1.2.1.11) is the enzyme that lies at the first branch point in the… (More)
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2010
2010
Expansion of the aspartate beta-semialdehyde dehydrogenase family: the first structure of a fungal ortholog.
The enzyme aspartate semialdehyde dehydrogenase (ASADH) catalyzes a critical transformation that produces the first branch-point… (More)
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2006
2006
Regulation of aspartokinase, aspartate semialdehyde dehydrogenase, dihydrodipicolinate synthase and dihydrodipicolinate reductase in Lactobacillus plantarum.
The use of a lysine-overproducing strain of Lactobacillus plantarum in food or feed fermentations may lead to the production of… (More)
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2002
2002
Overproduction, purification, and characterization of recombinant aspartate semialdehyde dehydrogenase from Arabidopsis thaliana.
In plant and microorganisms, aspartate semialdehyde dehydrogenase (ASDH) produces the branch point intermediate between the… (More)
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2001
2001
Active site analysis of the potential antimicrobial target aspartate semialdehyde dehydrogenase.
Aspartate-beta-semialdehyde dehydrogenase (ASADH) lies at the first branch point in the biosynthetic pathway through which… (More)
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1999
1999
Sequence analysis and expression of the aspartokinase and aspartate semialdehyde dehydrogenase operon from rifamycin SV-producing amycolatopsis mediterranei.
A approximately 4.8 kb KpnI fragment, from the upstream region of the methylmalonyl-CoA mutase gene (mutAB) of rifamycin SV… (More)
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1994
1994
Isolation and characterization of the aspartokinase and aspartate semialdehyde dehydrogenase operon from mycobacteria.
Diaminopimelic acid (DAP) is a major component of the peptidoglycan layer of the mycobacterial cell wall. The mycobacterial cell… (More)
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1990
1990
Aspartokinase genes lysCα and lysCβ overlap and are adjacent to the aspartate β-semialdehyde dehydrogenase gene asd in Corynebacterium glutamicum
SummaryA 2.1 kb DNA fragment of the recombinant plasmid pCS2, isolated from an aminoethyl cysteine (AEC)-resistant and lysine… (More)
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1982
1982
Expression of Streptococcus mutans aspartate-semialdehyde dehydrogenase gene cloned into plasmid pBR322.
Streptococcus mutans chromosomal DNA cloned into the vector plasmid pBR322 in Escherichia coli is able to complement the… (More)
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