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Aspartate-Semialdehyde Dehydrogenase

Known as: L-Aspartate-4-semialdehyde:NADP+ oxidoreductase (phosphorylating), Aldehyde Dehydrogenase, Semiaspartate, Dehydrogenase, Aspartate-Semialdehyde 
An enzyme that catalyzes the conversion of L-aspartate 4-semialdehyde, orthophosphate, and NADP+ to yield L-4-aspartyl phosphate and NADPH. EC 1.2.1… Expand
National Institutes of Health

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In BloodProcess of secretionantagonists & inhibitorsaspects of radiation effects
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Highly Cited
2009
Highly Cited
2009
Malonic semialdehyde reductase, succinic semialdehyde reductase, and succinyl-coenzyme A reductase from Metallosphaera sedula: enzymes of the autotrophic 3-hydroxypropionate/4-hydroxybutyrate cycle…
A 3-hydroxypropionate/4-hydroxybutyrate cycle operates during autotrophic CO(2) fixation in various members of the Crenarchaea… Expand
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2005
2005
Design, Synthesis and Analysis of Inhibitors of Bacterial Aspartate Semialdehyde Dehydrogenase
Unsaturated and fluorinated analogues of aspartyl‐β‐phosphate were synthesised as potential inhibitors of the bacterial enzyme… Expand
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2004
2004
Aspartokinase genes lysCα and lysCβ overlap and are adjacent to the aspartate β-semialdehyde dehydrogenase gene asd in Corynebacterium glutamicum
SummaryA 2.1 kb DNA fragment of the recombinant plasmid pCS2, isolated from an aminoethyl cysteine (AEC)-resistant and lysine… Expand
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2002
2002
Aspartyl Phosphonates and Phosphoramidates: The First Synthetic Inhibitors of Bacterial Aspartate‐Semialdehyde Dehydrogenase
The synthesis of methylene phosphonate, difluoromethylene phosphonate and phosphoramidate analogues of aspartyl phosphate… Expand
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2002
2002
Overproduction, purification, and characterization of recombinant aspartate semialdehyde dehydrogenase from Arabidopsis thaliana.
In plant and microorganisms, aspartate semialdehyde dehydrogenase (ASDH) produces the branch point intermediate between the… Expand
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2001
2001
Active site analysis of the potential antimicrobial target aspartate semialdehyde dehydrogenase.
Aspartate-beta-semialdehyde dehydrogenase (ASADH) lies at the first branch point in the biosynthetic pathway through which… Expand
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Highly Cited
2001
Highly Cited
2001
Control of the threonine-synthesis pathway in Escherichia coli: a theoretical and experimental approach.
A computer simulation of the threonine-synthesis pathway in Escherichia coli Tir-8 has been developed based on our previous… Expand
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Highly Cited
1994
Highly Cited
1994
Isolation and characterization of the aspartokinase and aspartate semialdehyde dehydrogenase operon from mycobacteria
Diaminopimelic acid (DAP) is a major component of the peptidoglycan layer of the mycobacterial cell wall. The mycobacterial cell… Expand
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Highly Cited
1991
Highly Cited
1991
Control of the Lysine Biosynthesis Sequence in Corynebacterium glutamicum as Analyzed by Overexpression of the Individual Corresponding Genes.
The gene cluster that codes for feedback-resistant aspartate kinase (lysCalpha and lysCbeta) and aspartate semialdehyde… Expand
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1982
1982
Expression of Streptococcus mutans aspartate-semialdehyde dehydrogenase gene cloned into plasmid pBR322.
Streptococcus mutans chromosomal DNA cloned into the vector plasmid pBR322 in Escherichia coli is able to complement the… Expand
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