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Ascorbic acid is an essential nutrient commonly regarded as an antioxidant. In this study, we showed that ascorbate at… Expand Ascorbate (ascorbic acid, vitamin C), in pharmacologic concentrations easily achieved in humans by i.v. administration… Expand Metal-induced toxicity and carcinogenicity, with an emphasis on the generation and role of reactive oxygen and nitrogen species… Expand Ascorbic acid (vitamin C) occurs physiologically as the ascorbate anion: a water-soluble antioxidant that is found throughout the… Expand To cope with environmental fluctuations and to prevent invasion by pathogens, plant metabolism must be flexible and dynamic… Expand An imbalance between oxidants and antioxidants in favour of the oxidants, potentially leading to damage, is termed ‘oxidative… Expand Trace levels of transition metals can participate in the metal-catalyzed Haber-Weiss reaction (superoxide-driven Fenton reaction… Expand Free radicals vary widely in their thermodynamic properties, ranging from very oxidizing to very reducing. These thermodynamic… Expand Metabolism, like other aspects of life, involves tradeoffs. Oxidant by-products of normal metabolism cause extensive damage to… Expand We have shown recently that the temporal order of antioxidant consumption in human blood plasma exposed to a constant flux of… Expand