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Aptamers, Peptide

Known as: Aptamers, Peptide [Chemical/Ingredient], Peptide Aptamers 
Peptide sequences, generated by iterative rounds of SELEX APTAMER TECHNIQUE, that bind to a target molecule specifically and with high affinity.
National Institutes of Health

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In BloodProcess of secretionagonistsantagonists & inhibitors

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TRIPalpha protein, S cerevisiae

Papers overview

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Highly Cited
2014
Highly Cited
2014
CFP10 and ESAT6 aptamers as effective Mycobacterial antigen diagnostic reagents.
Highly Cited
2011
Highly Cited
2011
Peptides and aptamers targeting HSP70: a novel approach for anticancer chemotherapy.
The inhibition of heat shock protein 70 (HSP70) is an emerging strategy in cancer therapy. Unfortunately, no specific inhibitors… 
2009
2009
Peptide aptamers in label-free protein detection: 2. Chemical optimization and detection of distinct protein isoforms.
The early detection and diagnosis of cancer lies central to successful treatment and improved patient outcome. Current techniques… 
Review
2004
Review
2004
The insulin like growth factor-1 receptor (IGF-1R) as a drug target: novel approaches to cancer therapy.
Highly Cited
2004
Highly Cited
2004
The interaction of specific peptide aptamers with the DNA binding domain and the dimerization domain of the transcription factor Stat3 inhibits transactivation and induces apoptosis in tumor cells.
The transcription factor signal transducer and activator of transcription (Stat) 3 is activated through the interleukin-6 family… 
Highly Cited
2002
Highly Cited
2002
Use of magnetic beads in selection and detection of biotoxin aptamers by electrochemiluminescence and enzymatic methods.
Systematic evolution of ligands by exponential enrichment (SELEX) was used to develop DNA ligands (aptamers) to cholera whole… 
Highly Cited
2000
Highly Cited
2000
Induction of apoptosis in human papillomaviruspositive cancer cells by peptide aptamers targeting the viral E6 oncoprotein.
Certain types of human papillomaviruses (HPVs) are closely linked to the development of human cancers. Herein, it is shown that… 
Highly Cited
1998
Highly Cited
1998
Targeting cyclin-dependent kinases in Drosophila with peptide aptamers.
Two-hybrid technology provides a simple way to isolate small peptide aptamers that specifically recognize and strongly bind to a… 
Highly Cited
1996
Highly Cited
1996
Genetic selection of peptide aptamers that recognize and inhibit cyclin-dependent kinase 2
A NETWORK of interacting proteins controls the activity of cyclin-dependent kinase 2 (Cdk2) (refs 1, 2) and governs the entry of… 
Highly Cited
1996
Highly Cited
1996
Anti-peptide aptamers recognize amino acid sequence and bind a protein epitope.
In vitro selection of nucleic acid binding species (aptamers) is superficially similar to the immune response. Both processes… 
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