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Antigens, CD58

Known as: Lymphocyte Function Associated Antigen-3, CD58 Antigens, CD58 
Glycoproteins with a wide distribution on hematopoietic and non-hematopoietic cells and strongly expressed on macrophages. CD58 mediates cell… 
National Institutes of Health

Related topics

Related topics

6 relations
CD58 wt AlleleIn Bloodaspects of radiation effectsphysiological aspects

Narrower (1)

Lymphocyte Function-Associated Antigen 3, human

Broader (1)

Receptors, Leukocyte-Adhesion

Papers overview

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1997
1997
Costimulation by B7-1 and LFA-3 targets distinct nuclear factors that bind to the interleukin-2 promoter: B7-1 negatively regulates LFA-3-induced NF-AT DNA binding
We have characterized the regulation of nuclear factors involved in transcriptional control of the interleukin-2 (IL-2) promoter… 
Highly Cited
1996
Highly Cited
1996
Molecular interaction between CD58 and CD2 counter-receptors mediates the ability of monocytes to augment T cell activation by IL-12.
IL-12 stimulates both T and NK cells and is pivotal in the development of the Th1 immune response. In this work, we show that an… 
Highly Cited
1995
Highly Cited
1995
Lipopolysaccharide Effectively Up‐Regulates B7‐1 (CD80) Expression and Costimulatory Function of Human Monocytes
The influence of lipopolysaccharide (LPS) and various cytokines on the expression of the costimulatory molecule B7‐1 and… 
1994
1994
Costimulation of human CD4+ T lymphocytes with B7 and lymphocyte function-associated antigen-3 results in distinct cell activation profiles.
This study describes the distinct roles of B7 and LFA-3 in the regulation of T cell responses. Activation of CD4+ T cells with… 
1992
1992
Structural and functional epitopes of the human adhesion receptor CD58 (LFA‐3)
CD58 (LFA‐3), a heavily glycosylated protein of 40–70 kDa, is expressed on a broad range of hematopoietic and non‐hematopoietic… 
Highly Cited
1991
Highly Cited
1991
Adhesion molecule expression in psoriatic skin lesions and the influence of cyclosporin A
Normal skin of healthy individuals and both lesional and uninvolved skin from patients with psoriasis before and after receiving… 
Highly Cited
1991
Highly Cited
1991
New monoclonal antibodies in CD44 and CD58: their use to quantify CD44 and CD58 on normal human erythrocytes and to compare the distribution of CD44 and CD58 in human tissues.
The cell-surface glycoproteins CD44 and CD58 are involved in cell adhesion reactions. In this paper 12 monoclonal antibodies in… 
Review
1989
Review
1989
The CD2-LFA-3 and LFA-1-ICAM pathways: relevance to T-cell recognition.
Highly Cited
1988
Highly Cited
1988
Biosynthesis and function of LFA-3 in human mutant cells deficient in phosphatidylinositol-anchored proteins.
Mutants that lack expression of phosphatidylinositol (PI)-anchored proteins were derived from the human B lymphoblastoid JY cell… 
Highly Cited
1987
Highly Cited
1987
Purified lymphocyte function‐associated antigen‐3 and T11 target structure are active in CD2‐mediated T cell stimulation
In this study we have used cells expressing LFA‐3 or T11TS, the human and sheep forms of the ligand of CD2, as well as the… 
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