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The numbers of airway CD8 and B lymphocytes are increased in COPD patients, suggesting an autoimmune process. CD4… Expand In vitro work has defined the TNF receptor family member CD27 as a T and B cell co-stimulatory molecule. Its activity is governed… Expand Azathioprine and 6-mercaptopurine are antimetabolite thiopurine drugs that play important roles in the treatment of leukemia and… Expand Feline immunodeficiency virus (FIV) induces a disease similar to acquired immunodeficiency syndrome (AIDS) in cats, yet in… Expand Human immunodeficiency virus (HIV)-specific CD8+ T cells persist in high frequencies in HIV-infected patients despite impaired… Expand Studies on human B cells have featured CD27 as a marker and mediator of the B cell response. We have studied CD27 expression and… Expand During immunosuppression, cytomegalovirus (CMV) can reactivate and cause serious clinical problems. Normally, abundant virus… Expand In contrast to the expression of other TNFR/TNF family members, expression of CD27 and its ligand CD70 is predominantly confined… Expand CD70 (CD27 ligand (CD27L)), CD153 (CD30L), and CD154 (CD40L) are members of the tumor necrosis factor family of costimulatory… Expand CD27, a member of the tumor necrosis factor (TNF) receptor family, binds to its ligand CD70, a member of the TNF family, and… Expand