Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Antibody to SCL-70

Known as: Anti-Topoisomerase I Antibody, Anti-Topoisomerase I, Scl 70 Antibody 
An anti-nuclear autoantibody that recognizes a 70 kDa fragment of DNA topoisomerase 1. It is associated with scleroderma.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
Importance Idiopathic inflammatory myopathies are heterogeneous in their pathophysiologic features and prognosis. The emergence… Expand
  • figure 1
  • figure 2
Is this relevant?
2013
2013
OBJECTIVE The objectives are to detect the frequency of sicca symptoms and Sjögren's syndrome (SS) in patients with systemic… Expand
Is this relevant?
2013
2013
Objective. To investigate B cell survival cytokine messenger RNA (mRNA) levels as biomarkers of idiopathic inflammatory… Expand
Is this relevant?
Highly Cited
2010
Highly Cited
2010
OBJECTIVE The current study was performed in order to determine the prevalence of different myositis-specific and myositis… Expand
  • table 1
  • table 2
  • table 3
  • figure 1
  • table 4
Is this relevant?
2010
2010
BACKGROUND Systemic sclerosis (SSc) is a rare autoimmune disease characterized by the presence of various autoantibodies… Expand
Is this relevant?
Highly Cited
2008
Highly Cited
2008
The aim of this study was to investigate the types and prevalence of disease-specific antinuclear antibodies (ANAs) and their… Expand
  • table 1
  • figure 1
  • table 2
  • table 3
  • figure 2
Is this relevant?
Review
2003
Review
2003
Systemic sclerosis (SSc) is a connective tissue disorder characterized by vascular abnormalities and excessive collagen synthesis… Expand
Is this relevant?
2001
2001
OBJECTIVE To investigate the presence and clinical significance of anti-Scl-70 antibodies in patients with systemic lupus… Expand
Is this relevant?
Highly Cited
1999
Highly Cited
1999
OBJECTIVE To determine the performance characteristics of enzyme-based immunoassay (EIA) kits for the detection of antinuclear… Expand
Is this relevant?
1990
1990
Anti-topoisomerase I autoantibodies (anti-topo I, anti-Scl-70) are associated with proximal scleroderma and are of prognostic… Expand
Is this relevant?