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Angiotensin I

Known as: 1 angiotensin, Angiotensin I [Chemical/Ingredient], angiotensin 1 
A decapeptide that is cleaved from precursor angiotensinogen by RENIN. Angiotensin I has limited biological activity. It is converted to angiotensin… 
National Institutes of Health

Related topics

Related topics

16 relations

Broader (2)

AGT geneAngiotensins
Angiotensin I:SCnc:Pt:Plas:QnAngiotensinogenIn BloodProcess of secretion

Narrower (3)

angiotensin I (1-7)angiotensin I (1-9)des-angiotensin I renin substrate

Papers overview

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Review
2006
Review
2006
Manipulating the angiotensin system – new approaches to the treatment of solid tumours
Angiotensin II (Ang II), a main effector peptide in the renin–angiotensin system (RAS), plays a fundamental role as a… 
Highly Cited
1998
Highly Cited
1998
Young SHR express increased type 1 angiotensin II receptors in renal proximal tubule.
A potential role for the renin-angiotensin system (RAS) in the development and/or maintenance of hypertension in the genetic… 
1998
1998
Regulation of vascular type 1 angiotensin II receptor in hypertension and sodium loading: role of angiotensin II
Objective To test the hypotheses that a high sodium intake increases steady state messenger RNA levels of the type 1 angiotensin… 
Highly Cited
1996
Highly Cited
1996
Drosophila melanogaster angiotensin I-converting enzyme expressed in Pichia pastoris resembles the C domain of the mammalian homologue and does not require glycosylation for secretion and enzymic…
Drosophila melanogaster angiotensin I-converting enzyme (AnCE) is a secreted single-domain homologue of mammalian angiotensin I… 
Highly Cited
1995
Highly Cited
1995
Increased Expression of Type 1 Angiotensin II Receptors in the Hypothalamic Paraventricular Nucleus following Stress and Glucocorticoid Administration
Double staining in situ hybridization studies have shown that angiotensin II (All) type 1 receptors (AT1) in the hypothalamic… 
1992
1992
Blocking hypothalamic AT1 receptors lowers blood pressure in salt-sensitive rats.
Previous studies from our laboratory have shown that microinjection of DuP 753 (2-n-butyl-4-chloro-5-(hydroxymethyl)-1-[[2'-(1H… 
Highly Cited
1981
Highly Cited
1981
Angiotensin II immunoreactivity coexists with renin in the juxtaglomerular granular cells of the kidney.
The multiple physiologic functions of angiotensin II(AII) are generally supposed to be mediated by the peptide generated in the… 
Highly Cited
1977
Highly Cited
1977
Trypsin‐Induced Activation of Renin Precursor in Plasma of Normal and Anephric Man
A two-stage incubation protocol has been employed to ascertain whether substantial trypsin-induced elevation of human plasma… 
Highly Cited
1977
Highly Cited
1977
Angiotensin I converting enzyme from human plasma.
The angiotensin I converting enzyme was purified 101 000-fold to homogeneity from human plasma by a combination of… 
Highly Cited
1958
Highly Cited
1958
THE SYNTHESIS OF A TETRADECAPEPTIDE RENIN SUBSTRATE
A tetradecapeptide renin substrate having a biological activity comparable to the natural product and similar chemical properties… 
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