Skip to search formSkip to main contentSkip to account menu

Angiogenic Switch

Loss of the balance between stimulation and inhibition of new blood vessel growth. A required early step in cancer growth and metastasis.
National Institutes of Health

Related topics

Related topics

1 relation
Tumor Angiogenesis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2014
Review
2014
Tumor dormancy and the angiogenic switch: possible implications of bone marrow- derived cells.
Although escape from tumor dormancy has long been recognized as an important problem in the treatment of cancer, the molecular… 
2011
2011
The Angiogenic Switch for Vascular Endothelial Growth Factor-A and Cyclooxygenase-2 in Prostate Carcinoma: Correlation with Microvessel Density, Androgen Receptor Content and Gleason Grade
Objective: Angiogenesis is essential for tumor growth and metastasis; however, angiogenic factors are not uniformly expressed in… 
2010
2010
Loss of p19Arf Facilitates the Angiogenic Switch and Tumor Initiation in a Multi-Stage Cancer Model via p53-Dependent and Independent Mechanisms
The Arf tumor suppressor acts as a sensor of oncogenic signals, countering aberrant proliferation in large part via activation of… 
2009
2009
Prostaglandin E2 Primes the Angiogenic Switch via a Synergic Interaction With the Fibroblast Growth Factor-2 Pathway
Rationale: Prostaglandin (PG)E2 exerts temporally distinct actions on blood vessels, immediate vasodilatation, and long-term… 
2007
2007
Angiogenic switch during tumor progression of carcinoma ex-pleomorphic adenoma
We analyzed the tumor vascularization in carcinomas ex-pleomorphic adenoma (CXPA) to investigate the angiogenic switch during the… 
2004
2004
The Edpm5 locus prevents the 'angiogenic switch' in an estrogen-induced rat pituitary tumor.
Edpm5 is one member of a group of quantitative trait loci that are responsible for the difference in susceptibility to estrogen… 
Highly Cited
2003
Highly Cited
2003
The transcription factor Net regulates the angiogenic switch.
Angiogenesis is fundamental to physiological and pathological processes. Despite intensive efforts, little is known about the… 
2002
2002
Inhibition of the mammary carcinoma angiogenic switch in C3(1)/SV40 transgenic mice by a mutated form of human endostatin
Cancer therapies based on the inhibition of angiogenesis by endostatin have recently been developed. We demonstrate that a… 
2001
2001
The human papillomavirus (HPV) 16 E6 oncoprotein leads to an increase in gene expression of the angiogenic switch molecule FGF-BP in non-immortalized human keratinocytes
Fibroblast growth factor binding protein (FGF-BP) is a secreted protein that binds FGF-1 and FGF-2 and is involved in… 
2000
2000
Salivary carcinoma in HER‐2/neu transgenic male mice: An angiogenic switch is not required for tumor onset and progression
Morphologic examinations of salivary gland neoplasias arising in male BALB/c (H‐2d) mice carrying the activated HER‐2/neu (BALB… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)