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Anethole Trithione

Known as: 3-(p-Methoxyphenyl)trithione, Anetholetrithione, 5-(p-Methoxyphenyl)-3H-1,2-dithiole-3-thione 
A substituted dithiolthione and analog of chemopreventive agent oltipraz. Anethole trithione is a bile secretion-stimulating drug that restores… Expand
National Institutes of Health

Related topics

Related topics

14 relations
Anethole Trithione / CholineIn BloodSialoragonists
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Narrower (4)

FelvitenSL-25SulfarlemTrithio

Broader (1)

anethole

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Age-related loss of hepatic Nrf2 protein homeostasis: Potential role for heightened expression of miR-146a.
Nrf2 regulates the expression of numerous anti-oxidant, anti-inflammatory, and metabolic genes. We observed that, paradoxically… Expand
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Highly Cited
2009
Highly Cited
2009
Lipid-based formulations to enhance oral bioavailability of the poorly water-soluble drug anethol trithione: effects of lipid composition and formulation.
This study has explored the use of lipid-based formulations to enhance the oral bioavailability of the poorly water-soluble drug… Expand
Highly Cited
2002
Highly Cited
2002
A randomized phase IIb trial of anethole dithiolethione in smokers with bronchial dysplasia.
BACKGROUND Results from preclinical studies have suggested that the organosulfur compound anethole dithiolethione (ADT) may be an… Expand
2002
2002
Usefulness of basal and pilocarpine-stimulated salivary flow in primary Sjögren's syndrome. Correlation with clinical, immunological and histological features.
OBJECTIVES To examine salivary function in patients with primary Sjögren's syndrome (SS) by assessing unstimulated and stimulated… Expand
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2000
2000
Significance of saliva for the denture-wearing population.
UNLABELLED This paper summarises a series of studies already published in German and presents new data related to the aetiology… Expand
2000
2000
Inhibition of aflatoxin M1 production by bovine hepatocytes after intervention with oltipraz
Abstract It is well known that cattle ingesting aflatoxin B1 contaminated feed commodities excrete aflatoxin M1 into their milk… Expand
1999
1999
Treatment of xerostomia with the bile secretion-stimulating drug anethole trithione: a clinical trial.
BACKGROUND Saliva protects the oral mucosa, inhibiting microbial overgrowth. Hyposalivation, therefore, induces multiple oral… Expand
Highly Cited
1999
Highly Cited
1999
Improvement in solubility and dissolution rate of 1, 2-dithiole-3-thiones upon complexation with beta-cyclodextrin and its hydroxypropyl and sulfobutyl ether-7 derivatives.
Inclusion complexes between beta-cyclodextrin derivatives and 1, 2-dithione-3-thiones were studied in aqueous solution and in the… Expand
1997
1997
A comparative study of the effects of yohimbine and anetholtrithione on salivary secretion in depressed patients treated with psychotropic drugs
AbstractObjective: The present study compares the effects of yohimbine, an alpha2 adrenoceptor antagonist, and anetholtrithione… Expand
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1996
1996
Pathways of metabolism of [1'-14C]-trans-anethole in the rat and mouse.
This study describes the metabolic fate of trans-4'-methoxyprop-[1-14C]enylbenzene, the natural flavor compound trans-anethole… Expand
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